Engineering Research Center of Active Substance Biotechnology, Ministry of Education, College of Life Sciences, Chongqing Normal University, Chongqing 401331, China.
College of Pharmacy, Chongqing Medical and Pharmaceutical College, Chongqing 401331, China.
Food Chem. 2025 Jan 15;463(Pt 3):141374. doi: 10.1016/j.foodchem.2024.141374. Epub 2024 Sep 21.
Herein, a novel chemiluminescence (CL) sensor was successfully developed based on chlorine doped carbon dots (Cl/CDs) for the rapid determination of bisphenol A (BPA) and nitrite. The Cl/CDs were synthesized through a hydrothermal method, using ascorbic acid as the precursor and hydrochloric acid as the dopant. It was found that Cl/CDs significantly enhanced the CL intensity of the acid-KMnO system, while BPA and nitrite quenched the CL intensity of the Cl/CDs-sensitized acid-KMnO system. Under optimal conditions, BPA exhibited a linear detection range of 0.05-10 μM, with limits of detection (LOD) and quantification (LOQ) of 0.86 nM and 2.8 nM, respectively. Nitrite showed a linear detection range of 0.7-100 μM, with LOD and LOQ of 22.5 nM and 75 nM, respectively. The CL sensor was successfully use to determine BPA in water samples and nitrite in pickles, ham and celery, with spike recovery rates of 96.3 %-104.8 % and 96.0 %-104.9 %, respectively.
本文报道了一种基于氯掺杂碳点（Cl/CDs）的新型化学发光（CL）传感器，用于快速测定双酚 A（BPA）和亚硝酸盐。Cl/CDs 通过水热法合成，以抗坏血酸为前驱体，盐酸为掺杂剂。结果表明，Cl/CDs 显著增强了酸性 KMnO4 体系的 CL 强度，而 BPA 和亚硝酸盐则猝灭了 Cl/CDs 敏化的酸性 KMnO4 体系的 CL 强度。在最佳条件下，BPA 的线性检测范围为 0.05-10 μM，检测限（LOD）和定量限（LOQ）分别为 0.86 nM 和 2.8 nM。亚硝酸盐的线性检测范围为 0.7-100 μM，LOD 和 LOQ 分别为 22.5 nM 和 75 nM。该 CL 传感器成功用于水样中 BPA 和泡菜、火腿和芹菜中亚硝酸盐的测定，回收率为 96.3%-104.8%和 96.0%-104.9%。
