Abuduruk Sarah H, Sabb Gul Bayan K, AlMasoudi Shuruq M, Alfattani Enas H, Mohammad Mouaz A, Alshehri Hind M, Alosaimi Ashwaq D, Almnjwami Rakan F, Alnafie Johara A, Jabbari Ali N, Althumali Abdulaziz H
Department of Otolaryngology, Alhada Armed Forces Hospital, Taif, SAU.
Department of Otolaryngology, Al-Noor Specialized Hospital, Makkah, SAU.
Cureus. 2024 Aug 27;16(8):e67910. doi: 10.7759/cureus.67910. eCollection 2024 Aug.
Chronic rhinosinusitis with nasal polyposis (CRSwNP) occurs due to the inflammation of sinonasal tissue. Cases of CRSwNP more commonly demand revision endoscopic sinus surgery (ESS) as compared to patients without polyposis. The recurrence rate varies widely depending on various factors, such as the extent of surgery, patient compliance with postoperative care, and the severity of the underlying disease. Studies conducted on chronic rhinosinusitis (CRS) patients showing recurrence or relapse of nasal polyps post endoscopic sinus surgery were included. We used the modified Newcastle-Ottawa scale (NOS) for cross-sectional studies and cohort studies. Only 15 articles met our inclusion and exclusion criteria after the full-text screening. The studies enrolled participants between 2009 and 2022, including 2,515 ESS patients. The mean age of the included subjects ranged between 37.1 and 57.57 years. In conclusion, CRSwNP is a chronic inflammatory disease that can impose a significant burden on patients, healthcare systems, and society. Asthma, aspirin intolerance, peripheral eosinophilia, interleukin-5 (IL-5) expression, T2 profile, and intense sinus opacification have been noted to be independent predictors of the condition in different studies. Recurrent polyposis in CRS signals a more aggressive disease course, requiring close follow-up and revision surgeries in the long run.
伴鼻息肉的慢性鼻-鼻窦炎（CRSwNP）是由于鼻窦组织炎症引起的。与无息肉的患者相比，CRSwNP患者更常需要进行内镜鼻窦手术（ESS）翻修。复发率因多种因素差异很大，如手术范围、患者对术后护理的依从性以及基础疾病的严重程度。纳入了对慢性鼻-鼻窦炎（CRS）患者进行的研究，这些研究显示内镜鼻窦手术后鼻息肉复发或再发。我们对横断面研究和队列研究使用改良的纽卡斯尔-渥太华量表（NOS）。全文筛选后，只有15篇文章符合我们的纳入和排除标准。这些研究纳入了2009年至2022年期间的参与者，包括2515例ESS患者。纳入受试者的平均年龄在37.1岁至57.57岁之间。总之，CRSwNP是一种慢性炎症性疾病，会给患者、医疗系统和社会带来重大负担。在不同研究中，哮喘、阿司匹林不耐受、外周嗜酸性粒细胞增多、白细胞介素-5（IL-5）表达、T2特征以及鼻窦严重混浊被认为是该疾病的独立预测因素。CRS中的复发性息肉表明疾病进程更具侵袭性，长期需要密切随访和翻修手术。
