Sidiq Sameer Akbar, Asad Usman, Ren Vicky
Baylor College of Medicine, Houston, TX, USA.
Department of Dermatology, Baylor College of Medicine, Houston, TX, USA.
Arch Dermatol Res. 2024 Sep 27;316(9):646. doi: 10.1007/s00403-024-03406-1.
Erythromelalgia is a rare condition with no published estimates of prevalence from a diverse, nationwide cohort of American patients. We performed a cross-sectional analysis of the All of Us database to estimate the prevalence of erythromelalgia overall and by age groups. Of 410,361 participants, 47 were diagnosed with erythromelalgia, representing an overall age-adjusted prevalence of 10.3 (95% CI 7.4-13.3) per 100,000 people. The prevalence was higher in the 65 + age group (16, 95% CI 9.5-23, per 100,000 people) than the less than 65 age group (9.1, 95% CI 5.5-13, per 100,000 people). Further studies are needed to determine the burden of erythromelalgia in specific subgroups, such as race, within the United States.
红斑性肢痛症是一种罕见病症，目前尚无来自美国不同地区全国性患者队列的患病率公开估计数据。我们对“我们所有人”数据库进行了横断面分析，以估计红斑性肢痛症的总体患病率以及按年龄组划分的患病率。在410361名参与者中，有47人被诊断患有红斑性肢痛症，总体年龄调整患病率为每10万人10.3例（95%置信区间7.4 - 13.3）。65岁及以上年龄组的患病率（每10万人16例，95%置信区间9.5 - 23）高于65岁以下年龄组（每10万人9.1例，95%置信区间5.5 - 13）。在美国，需要进一步研究以确定红斑性肢痛症在特定亚组（如种族）中的负担情况。
