Kalgaard O M, Seem E, Kvernebo K
Department of Dermatology, National Hospital Norwegian Research Council, Oslo, Norway.
J Intern Med. 1997 Sep;242(3):191-7. doi: 10.1046/j.1365-2796.1997.00185.x.
We report on aetiological factors, clinical findings and prognosis of 87 patients with erythromelalgia (EM). This is the largest material reported in the western literature. There is a 100% follow up of patients with observation period up to 11 years. There were 61 females and 26 males. About two-thirds of the patients were primary cases and around three-quarters had a chronic condition. The condition was more common in lower than in upper extremities. Over time patients with erythromelalgic syndrome gradually get worse, those with primary and secondary acute EM get better, whilst primary and secondary chronic EM remain stable.
我们报告了87例红斑性肢痛症（EM）患者的病因、临床症状及预后情况。这是西方文献中报道的最大样本。对患者进行了100%的随访，观察期长达11年。其中女性61例，男性26例。约三分之二的患者为原发性病例，约四分之三患有慢性病。该病在下肢比在上肢更常见。随着时间推移，红斑性肢痛症综合征患者病情逐渐加重，原发性和继发性急性EM患者病情好转，而原发性和继发性慢性EM患者病情保持稳定。
