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缩小差距：提出一个社会生态框架，使癌症临床试验对青少年和青年更易获得、更公平且更可接受。

Closing the gap: proposing a socio-ecological framework to make cancer clinical trials more accessible, equitable, and acceptable to adolescents and young adults.

作者信息

Ahmad Zeba, Venkataraman Vinayak, Markwart Michaela, Abrams Annah N, Temel Jennifer S, Perez Giselle K

机构信息

Health Promotion and Resiliency Intervention Research Center (HPRIR), Massachusetts General Hospital, Boston, MA 02114, United States.

Harvard Medical School, Boston, MA 02115, United States.

出版信息

Oncologist. 2024 Nov 4;29(11):918-921. doi: 10.1093/oncolo/oyae257.

DOI:10.1093/oncolo/oyae257
PMID:39331472
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11546816/
Abstract

This commentary focuses on what would make cancer clinical trials more accessible, equitable, and acceptable to adolescents and young adults.

摘要

本评论聚焦于如何使癌症临床试验对青少年和青年更易参与、更公平且更可接受。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7367/11546816/83c55d9d83cb/oyae257_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7367/11546816/83c55d9d83cb/oyae257_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7367/11546816/83c55d9d83cb/oyae257_fig1.jpg

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本文引用的文献

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Survival Trends Among Adolescents and Young Adults Diagnosed With Cancer in the United States: Comparisons With Children and Older Adults.美国诊断患有癌症的青少年和青年的生存趋势：与儿童和老年人的比较。
J Clin Oncol. 2024 Feb 20;42(6):630-641. doi: 10.1200/JCO.23.01367. Epub 2023 Oct 26.
2
Prevalence of Adverse Event Reporting in Adolescents and Young Adults Enrolled in Cancer Clinical Trials.青少年和青年癌症临床试验参与者中不良事件报告的流行率。
JCO Oncol Pract. 2023 Nov;19(11):1048-1052. doi: 10.1200/OP.23.00201. Epub 2023 Sep 25.
3
Creation of a quality improvement collaborative to address adolescent and young adult cancer clinical trial enrollment: ATAQI (AYA trial access quality initiative).
创建一个质量改进协作组织，以解决青少年和年轻成人癌症临床试验入组问题：ATAQI（AYA 试验入组质量倡议）。
Curr Probl Cancer. 2023 Dec;47(6):100898. doi: 10.1016/j.currproblcancer.2022.100898. Epub 2022 Sep 28.
4
Clinical Trial Participation: A Qualitative Study of Adolescents and Younger Adults Recently Diagnosed with Cancer.临床试验参与：一项最近被诊断患有癌症的青少年和年轻成年人的定性研究。
J Adolesc Young Adult Oncol. 2023 Jun;12(3):303-313. doi: 10.1089/jayao.2022.0050. Epub 2022 Jul 27.
5
Comparing Barriers and Facilitators to Adolescent and Young Adult Clinical Trial Enrollment Across High- and Low-Enrolling Community-Based Clinics.比较高和低招募社区诊所青少年和青年临床试验入组的障碍和促进因素。
Oncologist. 2022 May 6;27(5):363-370. doi: 10.1093/oncolo/oyac030.
6
Perspectives on Access to Novel Therapeutics Through Clinical Trials Among Adolescents and Young Adults with Advanced Cancer: Implications for Patient-Centered Clinical Trials.青少年和青年晚期癌症患者通过临床试验获得新型治疗方法的看法：对以患者为中心的临床试验的启示。
J Adolesc Young Adult Oncol. 2023 Feb;12(1):53-58. doi: 10.1089/jayao.2021.0152. Epub 2022 Mar 1.
7
Patterns of National Cancer Institute-Sponsored Clinical Trial Enrollment in Black Adolescents and Young Adults.国家癌症研究所资助的临床试验中黑人青少年和年轻成年人的入组模式。
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Adolescent and young adult enrollment to a National Cancer Institute-sponsored National Clinical Trials Network Research Group over 25 years.25 年来，青少年和年轻成年人参加美国国家癌症研究所资助的国家临床试验网络研究组的情况。
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