Department of Endocrinology, Shenzhen Longhua District Central Hospital, Shenzhen, Guangdong, China.
Medicine (Baltimore). 2024 Sep 27;103(39):e39771. doi: 10.1097/MD.0000000000039771.
Sjögren syndrome (SS) is a prevalent autoimmune disorder targeting exocrine glands, causing symptoms such as dry eyes and mouth. It often goes underdiagnosed due to its varied presentations, emphasizing the importance of early and accurate diagnosis.
A 22-year-old female presented with atypical symptoms of hypokalemic paralysis and severe bone pain, which are not commonly associated with SS.
Extensive diagnostic workup, including serological tests, ophthalmological assessments, and a lip biopsy, confirmed the diagnosis of distal renal tubular acidosis as a complication of SS.
The patient was treated with an intensive inpatient regimen designed to stabilize her potassium levels and alleviate her symptoms.
The comprehensive therapeutic intervention was successful, with the patient's symptoms being alleviated within 2 weeks.
This case underscores the importance of being aware of SS in younger demographics and the necessity for a prompt and multifaceted treatment approach to manage systemic effects and improve quality of life.
干燥综合征（SS）是一种常见的自身免疫性疾病，主要累及外分泌腺体，引起眼干、口干等症状。由于其临床表现多样，常被漏诊或误诊，强调了早期准确诊断的重要性。
一名 22 岁女性以低钾性瘫痪和严重骨痛为主要表现，这些症状不常见于 SS。
经过广泛的诊断检查，包括血清学检查、眼科评估和唇活检，最终确诊为 SS 并发远端肾小管酸中毒。
患者接受了强化住院治疗方案，以稳定血钾水平并缓解症状。
综合治疗干预成功，患者的症状在 2 周内得到缓解。
该病例强调了在年轻人群中注意 SS 的重要性，以及需要及时采取多方面的治疗方法来管理全身影响，提高生活质量。
