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干燥综合征合并范科尼综合征和桥本甲状腺炎：病例报告及文献复习

Sjögren's syndrome complicated with Fanconi syndrome and Hashimoto's thyroiditis: Case report and literature review.

作者信息

Shi Mingmin, Chen Lei

机构信息

Department of Orthopaedics, 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.

Department of Endocrinology and Metabolism, Sir Run Run Shaw Hospital Affiliated with the School of Medicine, Zhejiang University, Hangzhou, China

出版信息

J Int Med Res. 2016 Jun;44(3):753-9. doi: 10.1177/0300060515593767. Epub 2016 Mar 9.

DOI:10.1177/0300060515593767
PMID:26966155
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5536691/
Abstract

We report a unique case of Sjögren's syndrome complicated with Fanconi syndrome and Hashimoto's thyroiditis in a 53-year-old Chinese woman, initially found to have proteinuria, fatigue and multiple old costal fractures. Distal tubular dysfunction is the most common renal damage in Sjögren's syndrome, while Fanconi syndrome (which is caused by proximal tubular dysfunction) and Hypothyroidism are rare complications of Sjögren's syndrome.

摘要

我们报告了一例独特的病例，一名53岁的中国女性患干燥综合征，并伴有范科尼综合征和桥本甲状腺炎，最初发现有蛋白尿、疲劳和多处陈旧性肋骨骨折。远端肾小管功能障碍是干燥综合征最常见的肾脏损害，而范科尼综合征（由近端肾小管功能障碍引起）和甲状腺功能减退是干燥综合征罕见的并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a833/5536691/1dfc9772a48f/10.1177_0300060515593767-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a833/5536691/28a6f33e4893/10.1177_0300060515593767-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a833/5536691/c6b1778fa98d/10.1177_0300060515593767-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a833/5536691/1dfc9772a48f/10.1177_0300060515593767-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a833/5536691/28a6f33e4893/10.1177_0300060515593767-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a833/5536691/c6b1778fa98d/10.1177_0300060515593767-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a833/5536691/1dfc9772a48f/10.1177_0300060515593767-fig3.jpg

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