肠道微生物群与眼部疾病：综述
Gut microbiota and eye diseases: A review.
机构信息
School of Public Health, Hangzhou Medical College, Hangzhou, China.
Eye Center, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
出版信息
Medicine (Baltimore). 2024 Sep 27;103(39):e39866. doi: 10.1097/MD.0000000000039866.
Recent studies reveal that alterations in gut microbiota play a significant role in the progression of various diseases, including those affecting the eyes. The association between gut microbiota and eye health is an emerging focus of research. This review seeks to summarize the connection between the gut microbiome and specific eye conditions, such as ocular surface diseases, funduscopic disorders and immune-mediated eye diseases. Gut microbiota may influence these conditions by regulating the immune system or altering metabolites, thereby contributing to disease development. Strategies like probiotics, antibiotics, dietary modifications, and fecal transplants show promise in addressing these issues. This review examines how the gut microbiome may be linked to the pathogenesis of eye diseases, providing fresh therapeutic perspectives for ophthalmology.
最近的研究表明，肠道微生物群的改变在各种疾病的进展中起着重要作用，包括影响眼睛的疾病。肠道微生物群与眼睛健康之间的联系是研究的一个新兴焦点。本综述旨在总结肠道微生物组与特定眼部疾病（如眼表面疾病、眼底疾病和免疫介导的眼病）之间的联系。肠道微生物群可能通过调节免疫系统或改变代谢物来影响这些疾病的发生，从而促进疾病的发展。益生菌、抗生素、饮食改变和粪便移植等策略在解决这些问题上显示出了希望。本综述探讨了肠道微生物组如何与眼部疾病的发病机制相关联，为眼科学提供了新的治疗视角。
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