Barlas Aziz Mutlu, Altıner Saygın, Başpınar Abdurrahman, Aydın Seyit Murat, Doğanay Enes, Kaymak Şahin, Ünal Yılmaz
Ankara Training and Research Hospital, Department of General Surgery, Ankara, Turkey.
University of Health Scienece Gülhane Medical, School Department of General Surgery, Ankara, Turkey.
Asian J Surg. 2024 Sep 26. doi: 10.1016/j.asjsur.2024.09.091.
HALP score is a scoring system consisting of hemoglobin, albumin, lymphocyte and platelet. It is different from other prognostic markers because it provides information about both inflammation and immunonutrition status. This study aims to evaluate the severity of the disease and the level of prognosis in patients diagnosed with acute diverticulitis.
190 patients diagnosed with acute diverticulitis between January 2017 and June 2023 were included in the study. The patients were divided into two separate groups according to the Hinchey classification. The prognostic effect of inflammatory markers and HALP score was examined.
The median values of C-reactive protein, white blood cell count, neutrophil count, HALP score, and hospitalization duration were significantly higher in patients diagnosed with complicated diverticulitis than in those diagnosed with uncomplicated diverticulitis. (p < 0.001, p = 0.045, p = 0.004, p < 0.001 and p < 0.001, respectively). The distinguishing feature of the HALP score in predicting the complexity of the diagnosis of diverticulitis was evaluated using ROC analysis. Area Under Curve (AUC) value was found to be 0.723 (p < 0.001). According to the ROC curve, the sensitivity and specificity for the cut-off value of HALP score ≤44.1 were 66.7 % and 75.0 %, respectively.
HALP score is an inexpensive parameter that can be used safely to determine the severity and prognosis of acute diverticulitis.
HALP评分是一种由血红蛋白、白蛋白、淋巴细胞和血小板组成的评分系统。它与其他预后标志物不同，因为它提供了有关炎症和免疫营养状态的信息。本研究旨在评估诊断为急性憩室炎患者的疾病严重程度和预后水平。
本研究纳入了2017年1月至2023年6月期间诊断为急性憩室炎的190例患者。根据欣奇分类将患者分为两个独立的组。检查炎症标志物和HALP评分的预后效果。
诊断为复杂性憩室炎的患者中，C反应蛋白、白细胞计数、中性粒细胞计数、HALP评分和住院时间的中位数显著高于诊断为非复杂性憩室炎的患者。（分别为p < 0.001、p = 0.045、p = 0.004、p < 0.001和p < 0.001）。使用ROC分析评估HALP评分在预测憩室炎诊断复杂性方面的显著特征。曲线下面积（AUC）值为0.723（p < 0.001）。根据ROC曲线，HALP评分≤44.1的临界值的敏感性和特异性分别为66.7%和75.0%。
HALP评分是一种廉价的参数，可安全用于确定急性憩室炎的严重程度和预后。
