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[聚焦高能体外冲击波疗法(ESWT)治疗前臂和手部骨愈合障碍]

[Focused High-Energy Extracorporeal Shock Wave Therapy (ESWT) for Bone healing Disorders of the Forearm and the Hand].

作者信息

Liedl Eva-Kristina, van Schoonhoven Jörg, Prommersberger Karl-Josef, Mühldorfer-Fodor Marion

机构信息

Klinik für Handchirurgie, Rhön Klinikum Campus Bad Neustadt, Bad Neustadt, Germany.

出版信息

Handchir Mikrochir Plast Chir. 2024 Sep;56(5):350-358. doi: 10.1055/a-2406-5858. Epub 2024 Sep 27.

Abstract

BACKGROUND

ESWT is a non-surgical treatment option but can also be used in addition to surgical treatment (stabilisation, freshening, defect filling, removal of discomforting osteosynthesis material) for the treatment of delayed bone healing (DBH) and non-union (NU). Its value as well as influencing factors on the upper extremity have not been adequately quantified so far.

PATIENTS AND METHODS

Sixty cases were retrospectively studied after application of focused high-energy ESWT with regard to healing rate and consolidation time. The influence of age, location, time of treatment and treatment prior to and concurrent with ESWT were analysed.

RESULTS

In 70% of the cases, healing occurred after a median of 2.4 months (DBH) and 2.8 months (NU). The median age of healed (DBH 44 y., non-union 35 y.) and non-healed (DBH 51 y., NU 37 y.) did not differ significantly. The time between trauma/surgery and ESWT was 4.2 months for DBH in healed and 3.7 months in non-healed without a significant difference, and 27 months for NU in both healed and non-healed. Age and smoking status also had no influence. The healing rate was highest at metacarpal bone/finger/thumb (91%), followed by forearm shaft (88%), epiphysis/metaphysis of the forearm (67%), and, lastly, carpal bones (59%). After conservative pre-treatment, 55% healed, compared with 67% after more than two previous surgeries, 73% without any pre-treatment, and 75% after one previous surgery. Further analysis of surgical pre-treatment showed 85% healing after ORIF alone, 64% without previous surgery, and 57% healing after ORIF with bone grafting/debridement. Intraoperative ESWT combined with bone debridement/transplantation and ORIF resulted in 67% healing, compared with 86% in combination with ORIF alone. ESWT alone or with only minimal measures (removal of osteosynthesis material) led to 70% consolidation.

CONCLUSION

ESWT is equally effective at any stage of a bone healing disorder. The principles of stability and filling of bone defects must also be taken into account when using ESWT; then ESWT alone or combined with surgery is equally effective. The negative influence of bone defects/resorption is still detectable even with ESWT. Furthermore, treatment of the scaphoid is more problematic compared with other locations. Previous surgery is not a negative factor, even with osteosynthesis material in situ.

摘要

背景

体外冲击波疗法(ESWT)是一种非手术治疗选择,但也可在手术治疗(固定、清创、缺损填充、去除引起不适的内固定材料)的基础上用于治疗延迟骨愈合(DBH)和骨不连(NU)。其在上肢的价值及影响因素目前尚未得到充分量化。

患者与方法

回顾性研究了60例接受聚焦高能ESWT治疗后的病例,分析其愈合率和骨痂形成时间。分析了年龄、部位、治疗时间以及ESWT治疗前和治疗期间的治疗情况的影响。

结果

70%的病例在中位时间2.4个月(DBH)和2.8个月(NU)后实现愈合。愈合患者(DBH为44岁,骨不连为35岁)和未愈合患者(DBH为51岁,骨不连为37岁)的中位年龄无显著差异。愈合组DBH患者创伤/手术后至ESWT的时间为4.2个月,未愈合组为3.7个月,差异无统计学意义;愈合组和未愈合组骨不连患者的该时间均为27个月。年龄和吸烟状况也无影响。掌骨/手指/拇指部位的愈合率最高(91%),其次是前臂骨干(88%)、前臂骨骺/干骺端(67%),最后是腕骨(59%)。保守预处理后,55%实现愈合;相比之下,之前接受过两次以上手术的患者愈合率为67%,未接受任何预处理的患者愈合率为73%,接受过一次手术的患者愈合率为75%。对手术预处理的进一步分析显示,单纯切开复位内固定(ORIF)后愈合率为85%,未接受过手术的患者愈合率为64%,ORIF联合植骨/清创后愈合率为57%。术中ESWT联合骨清创/移植和ORIF的愈合率为67%,而仅联合ORIF的愈合率为86%。单纯ESWT或仅采取最小措施(去除内固定材料)导致70%的骨痂形成。

结论

ESWT在骨愈合障碍的任何阶段均同样有效。使用ESWT时还必须考虑骨缺损的稳定性和填充原则;此时,单纯ESWT或联合手术同样有效。即使采用ESWT,骨缺损/吸收的负面影响仍可检测到。此外,与其他部位相比,舟骨的治疗更具挑战性。既往手术并非负面因素,即使内固定材料仍在位。

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