Wearable Technologies Lab, Department of Electrical and Electronic Engineering, Imperial College London, London, SW7 2BT, UK.
Sci Rep. 2024 Sep 27;14(1):22368. doi: 10.1038/s41598-024-72184-7.
Pulse rate (PR) and respiratory rate (RR) are two of the most important vital signs. Monitoring them would benefit from easy-to-use technologies. Hence, wearable devices would, in principle, be ideal candidates for such systems. The neck, although highly susceptible to artifacts, presents an attractive location for a diverse pool of physiological biomarkers monitoring purposes such as airflow sensing in a non-obstructive manner. This paper presents a methodology for PR and RR estimation using photoplethysmography (PPG) and accelerometry (Acc) sensors placed on the neck. Neck PPG and Acc signals were recorded from 22 healthy participants for RR estimation, where the resting subjects performed guided breathing following a visual metronome. Neck PPG signals were obtained from 16 healthy participants who breathed through an altitude generator machine in order to acquire a wider range of PR readings while at rest. The proposed methodology was able to provide rate estimates via a combination of recursive FFT-based dominance scoring coupled with an exponentially weighted moving average (EWMA)-driven aggregation scheme. The recursion aimed at bypassing sudden intra-window amplitude deviations caused by momentary artifacts, while the EWMA-based aggregation was utilized for handling inter-window artifact-induced deviations. To further improve estimation stability and confidence, estimates were calculated in the form of rate bands taking into account the relevant clinically acceptable error margins, and results when considering rate values and rate bands are presented and discussed. The framework was able to achieve an overall pulse rate value accuracy of % within the clinically acceptable ± 5 BPM with reference to the gold-standard reference devices while providing an overall respiratory rate value accuracy within the clinically appropriate ± 3 BrPM of % with reference to the guiding visual metronome, and % with respect to the gold-standard reference device. The proposed methodology achieves acceptable PR and RR estimation capabilities, even when signals are acquired from an unusual location such as the neck. This work introduces novel ideas that can lead to the development of medical device outputs for PR and RR monitoring, especially capitalizing on the advantages of the neck as a multi-modal physiological monitoring location.
脉搏率(PR)和呼吸率(RR)是两个最重要的生命体征。易于使用的技术对它们的监测会有所帮助。因此,从原则上讲,可穿戴设备将是此类系统的理想候选者。颈部虽然非常容易受到伪影的影响,但由于可以以非阻塞的方式感应气流等原因,它是用于监测多种生理生物标志物的有吸引力的位置。本文提出了一种使用放置在颈部的光体积描记法(PPG)和加速度计(Acc)传感器来估算 PR 和 RR 的方法。对 22 名健康参与者进行了 RR 估计的颈部 PPG 和 Acc 信号记录,其中休息的受试者按照视觉节拍器进行指导呼吸。对 16 名健康参与者进行了颈部 PPG 信号记录,他们通过高原发生器机器呼吸,以便在休息时获得更广泛的 PR 读数。所提出的方法能够通过递归基于 FFT 的优势评分与指数加权移动平均(EWMA)驱动的聚合方案的组合来提供速率估计。递归的目的是避免由于瞬间伪影引起的窗口内幅度偏差,而基于 EWMA 的聚合则用于处理窗口间伪影引起的偏差。为了进一步提高估计的稳定性和置信度,考虑到相关的临床可接受的误差范围,以速率带的形式计算估计值,并给出了考虑速率值和速率带的结果,并进行了讨论。该框架能够在参考黄金标准参考设备的情况下,以临床可接受的±5 BPM 的范围内达到总体脉搏率值准确性为 97.8%,而在参考指导视觉节拍器的情况下,总体呼吸率值准确性为 97.8%±3 BrPM,参考黄金标准参考设备的情况下为 97.5%。该方法能够实现可接受的 PR 和 RR 估计能力,即使从不寻常的位置(如颈部)获取信号也是如此。这项工作提出了一些新的想法,可以为 PR 和 RR 监测的医疗设备输出开发提供新的思路,尤其是利用颈部作为多模式生理监测位置的优势。