伴有系统性红斑狼疮的双侧假性 Purtcher 样视网膜病变：病例报告
Simultaneous bilateral purtscher like retinopathy with systemic lupus erythematosus: a case.
机构信息
Department of Ophthalmology, West China Hospital, Sichuan University, Sichuan, China.
Department of Ophthalmology, West China Hospital of Sichuan University, No.37 guoxue Lane, Wuhou District, Chengdu city, Sichuan Province, China.
出版信息
BMC Ophthalmol. 2024 Sep 27;24(1):418. doi: 10.1186/s12886-024-03690-5.
BACKGROUD
Systemic lupus erythematosus is an unexplained autoimmune disease involving multiple systems throughout the body, and its ocular changes include dry eye, monocular or binocular visual field defects, vaso-occlusive diseases, or ischemic optic neuropathy.
CASE PRESENTATION
This article reports a patient with SLE complicated with bilateral Purtscher like retinopathy, who had a sudden decrease in ocular vision as the first symptom, the autoantibodies related to phospholipid syndrome showed no abnormality, and both anti-dsDNA antibodies and anti-SM antibodies were significantly positive, indicating that anti-dsDNA antibodies and anti-SM antibodies were also important factors in the pathogenesis of Purtscher like retinopathy.
CONCLUSION
The close relationship between SLE retinopathy and systemic inflammatory activities and emphasize the importance of systemic immunotherapy.
背景
系统性红斑狼疮是一种原因不明的自身免疫性疾病，涉及全身多个系统，其眼部改变包括干眼症、单眼或双眼视野缺损、血管阻塞性疾病或缺血性视神经病变。
病例介绍
本文报告了一例 SLE 合并双眼 Purtscher 样视网膜病变患者，以视力突然下降为首发症状，与磷脂综合征相关的自身抗体无异常，抗 dsDNA 抗体和抗 SM 抗体均明显阳性，表明抗 dsDNA 抗体和抗 SM 抗体也是 Purtscher 样视网膜病变发病机制的重要因素。
结论
SLE 视网膜病变与全身炎症活动密切相关，强调了全身免疫治疗的重要性。
Zotero 插件