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低收入国家双侧先天性和青少年白内障的管理:患者识别、治疗结果及随访

Management of Bilateral Congenital and Juvenile Cataracts in a Low-Income Country: Patient Identification, Treatment Outcomes, and Follow Up.

作者信息

Poschkamp Broder, Dinkulu Serge, Stahnke Thomas, Böckermann Clara, Mukwanseke Edith, Paschke Christiane, Hopkins Adrian, Duerksen Rainald, Steinau Ellen Catrin, Stahl Andreas, Götz Andreas, Guthoff Rudolf, Kilangalanga Ngoy-Janvier

机构信息

Department of Ophthalmology, University Medicine Greifswald, Ferdinand-Sauerbruch-Street, 17475 Greifswald, Germany.

St. Joseph Hospital Kinshasa, J8MR+HCR, Kinshasa, Democratic Republic of the Congo.

出版信息

Children (Basel). 2024 Aug 30;11(9):1064. doi: 10.3390/children11091064.

Abstract

BACKGROUND

Childhood blindness remains a neglected issue in eye care within low-income countries, with congenital and juvenile cataracts being the most common treatable causes. This study aims to investigate the factors influencing the management of congenital and juvenile bilateral cataracts, provide data on general outcomes and postoperative findings, and discuss treatment in a low-income country context.

METHODS

In this prospective study, data from clinical care were continuously entered into a database, and one follow-up examination of a cohort of 91 patients with congenital and juvenile bilateral cataracts in Kinshasa, Democratic Republic of the Congo, was conducted. Multiple factors that affect the first clinical presentation, the clinical management, and outcome were investigated.

RESULTS

Most patients (88.5%) who received medical treatment were identified by cataract finders. A patient's presentation time was independent of the parent's education, social status, income, and sex of the child. The median age at first presentation was 5.8 years (ranging from 0 days to 17.3 years). The best visual acuity outcomes were achieved by patients who underwent surgery during early childhood. According to WHO grades and on an eye level basis, 51.1% (93 out of 182 eyes) showed improvement, while 34.6% (63 eyes) had unchanged results post-surgery. Among the cases without improvement, 76.2% were blind prior to surgery. Postoperative findings were observed in 56% of the patients, with secondary cataracts being the most common, affecting 26.37% of the operated eyes.

CONCLUSIONS

Optimal management of childhood cataracts involves early identification, efficient hospital infrastructure, high-quality medical care, and long-term follow up. In sub-Saharan Africa, this approach must be adapted to the context of available resources, which differs significantly from those in high- and middle-income countries.

摘要

背景

在低收入国家的眼保健中,儿童失明仍是一个被忽视的问题,先天性和青少年白内障是最常见的可治疗病因。本研究旨在调查影响先天性和青少年双侧白内障治疗的因素,提供总体结果和术后检查数据,并在低收入国家背景下讨论治疗方法。

方法

在这项前瞻性研究中,临床护理数据被持续录入数据库,并对刚果民主共和国金沙萨的91例先天性和青少年双侧白内障患者进行了一次随访检查。调查了影响首次临床表现、临床治疗及结果的多种因素。

结果

大多数接受治疗的患者(88.5%)是由白内障筛查人员发现的。患者的就诊时间与父母的教育程度、社会地位、收入及孩子的性别无关。首次就诊的中位年龄为5.8岁(范围从0天至17.3岁)。幼儿期接受手术的患者获得了最佳视力结果。根据世界卫生组织分级并以眼为单位,51.1%(182只眼中的93只)术后视力有改善,而34.6%(63只眼)术后结果未变。在未改善的病例中,76.2%在手术前已失明。56%的患者有术后检查结果,其中继发性白内障最常见,影响了26.37%的手术眼。

结论

儿童白内障的最佳治疗包括早期识别、高效的医院基础设施、高质量的医疗护理及长期随访。在撒哈拉以南非洲,这种方法必须适应可用资源的情况,这与高收入和中等收入国家有很大不同。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8d7/11430800/3180b5ac616f/children-11-01064-g001.jpg

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本文引用的文献

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Complications of manual small-incision cataract surgery.
Indian J Ophthalmol. 2022 Nov;70(11):3803-3811. doi: 10.4103/ijo.IJO_1812_22.
2
Lens-Induced Glaucoma: An Audit of Cataract Cases in Hospital Sultanah Nur Zahirah, Kuala Terengganu (HSNZKT).
Cureus. 2022 Mar 5;14(3):e22875. doi: 10.7759/cureus.22875. eCollection 2022 Mar.
3
Identification of amblyogenic risk factors with the Brückner reflex test using the low-cost Arclight direct ophthalmoscope.
Eye (Lond). 2021 Nov;35(11):3007-3011. doi: 10.1038/s41433-020-01341-9. Epub 2021 Jan 7.
5
Neural mechanisms of visual sensitive periods in humans.
Neurosci Biobehav Rev. 2021 Jan;120:86-99. doi: 10.1016/j.neubiorev.2020.10.030. Epub 2020 Nov 23.
7
An electrophysiological biomarker for the classification of cataract-reversal patients: A case-control study.
EClinicalMedicine. 2020 Oct 6;27:100559. doi: 10.1016/j.eclinm.2020.100559. eCollection 2020 Oct.
9
Role of a Community-based Program for Identification and Referral of Pediatric Cataract Patients in Kinshasa, Democratic Republic of the Congo.
Middle East Afr J Ophthalmol. 2019 Aug 26;26(2):83-88. doi: 10.4103/meajo.MEAJO_273_18. eCollection 2019 Apr-Jun.
10
Delay in presentation to hospital for childhood cataract surgery in India.
Eye (Lond). 2018 Dec;32(12):1811-1818. doi: 10.1038/s41433-018-0176-2. Epub 2018 Jul 30.

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