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使用低成本的 Arclight 直视检眼镜进行 Brückner 反射测试,以确定致弱视风险因素。

Identification of amblyogenic risk factors with the Brückner reflex test using the low-cost Arclight direct ophthalmoscope.

机构信息

Royal Victoria Infirmary, Newcastle Upon Tyne, England.

University of St Andrews, School of Medicine, St Andrews, Scotland.

出版信息

Eye (Lond). 2021 Nov;35(11):3007-3011. doi: 10.1038/s41433-020-01341-9. Epub 2021 Jan 7.

Abstract

BACKGROUND/OBJECTIVES: The Arclight is a novel, low-cost, solar-powered direct ophthalmoscope developed for low resource settings as an alternative to more expensive, conventional devices. The Brückner reflex test (BRT) is a quick and effective means to screen for eye disease and amblyogenic risk factors. This test is however rarely performed in low resource settings due to the lack of access to ophthalmoscopes and trained health care workers. Our aim was to establish the sensitivity and specificity of the BRT when performed by a non-expert using an Arclight and compare to an expert as well as the results of a full clinic workup.

SUBJECTS/METHODS: In this prospective, blinded study, 64 patients referred to a paediatric ophthalmology clinic had the BRT performed by a 'non-expert' observer (medical student) then an 'expert' observer (consultant ophthalmologist). These results were then compared against the 'gold standard' outcomes of a full clinical workup.

RESULTS

BRT screening by the expert observer led to a sensitivity of 75.0% [95% CI: 57.9-86.8%] and a specificity of 90.6% [95% CI: 75.8-96.8%] in picking up media opacity, strabismus, refractive error or a combination of the above. For the non-expert, the sensitivity and specificity were 71.9% [95% CI: 54.6-84.4%] and 84.4% [95% CI: 68.3-93.1%], respectively.

CONCLUSIONS

The Arclight can be effectively used to perform the BRT and identify eye disease and common amblyogenic risk factors. Even when performed by a non-expert the results are highly specific and moderately sensitive. This study consequently offers support for the use of this low-cost ophthalmoscope in the expansion of eye screening by health care workers in low resource settings.

摘要

背景/目的:Arclight 是一种新型的、低成本的、太阳能驱动的直接检眼镜,专为资源匮乏环境设计,是更昂贵的传统设备的替代产品。Brückner 反射测试(BRT)是一种快速有效的筛查眼部疾病和致弱视危险因素的方法。然而,由于缺乏检眼镜和经过培训的卫生保健工作者,该测试在资源匮乏环境中很少进行。我们的目的是确定非专业人员使用 Arclight 进行 BRT 的灵敏度和特异性,并将其与专家以及全面临床检查的结果进行比较。

方法

在这项前瞻性、盲法研究中,64 名转诊至儿科眼科诊所的患者由一名“非专家”(医学生)进行 BRT 检查,然后由一名“专家”(顾问眼科医生)进行检查。然后将这些结果与全面临床检查的“金标准”结果进行比较。

结果

专家观察者进行的 BRT 筛查在发现眼部混浊、斜视、屈光不正或上述多种情况的灵敏度为 75.0%[95%置信区间:57.9-86.8%],特异性为 90.6%[95%置信区间:75.8-96.8%]。对于非专家观察者,灵敏度和特异性分别为 71.9%[95%置信区间:54.6-84.4%]和 84.4%[95%置信区间:68.3-93.1%]。

结论

Arclight 可有效地用于进行 BRT,并识别眼部疾病和常见的致弱视危险因素。即使由非专业人员进行,结果也具有高度的特异性和中度的敏感性。因此,这项研究支持在资源匮乏环境中,卫生保健工作者使用这种低成本检眼镜来扩大眼部筛查。

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