Marcianò Gianmarco, Vocca Cristina, Dıraçoğlu Demirhan, Sevgin Rotinda Özdaş, Gallelli Luca
Operative Unit of Pharmacology and Pharmacovigilance, "Renato Dulbecco" University Hospital, 88100 Catanzaro, Italy.
Department of Physical Medicine and Rehabilitation, Istanbul Faculty of Medicine, Istanbul University, 34093 Istanbul, Türkiye.
Antioxidants (Basel). 2024 Sep 19;13(9):1130. doi: 10.3390/antiox13091130.
Escin, extracted from horse chestnut () has anti-edema and anti-inflammatory effects. It is used to treat several clinical conditions, including venous insufficiency, pain, inflammation, and edema. Considering escin's pharmacodynamic, the inhibition of the bradykinin pathway represents a particular effect, decreasing the local edema and conferring an advantage in comparison to other compounds. In this narrative review, we described the effects of escin considering its effects on bradykinin pathway.
七叶皂苷，从欧洲七叶树（）中提取，具有抗水肿和抗炎作用。它被用于治疗多种临床病症，包括静脉功能不全、疼痛、炎症和水肿。考虑到七叶皂苷的药效学，抑制缓激肽途径是其一种特殊作用，可减轻局部水肿，与其他化合物相比具有优势。在这篇叙述性综述中，我们描述了七叶皂苷对缓激肽途径的影响。
