Maghiar Laura, Sandor Mircea, Sachelarie Liliana, Bodog Ruxandra, Huniadi Anca
Department of Surgical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410073 Oradea, Romania.
Preclinical Sciences Department, Faculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410073 Oradea, Romania.
Biomedicines. 2024 Sep 13;12(9):2098. doi: 10.3390/biomedicines12092098.
This narrative review provides a comprehensive analysis of skin lesions caused by human papillomavirus (HPV). Human papillomavirus is an infection involving a virus that is omnipresent and can range from benign wart lesions to malignant skin growths. This review includes an analysis of the skin manifestations caused by HPV, and the need for continued successful diagnostic techniques and treatment methods, given the increasing rates of infection among people worldwide. We reviewed all 135 studies related to pathophysiology involving skin, risk factors, and early detection methods like biopsy and molecular testing, from 2000 to 2023. The current treatments, including cryotherapy and laser therapy, are discussed, while the review emphasizes the role of HPV vaccination in preventing infection. Recommendations for the future would involve the improvement of public education and increased vaccine coverage, together with innovative therapies toward better management or control of skin diseases associated with the human papillomavirus (HPV). By advancing these recommendations, we will be in a better position to prevent and treat HPV skin conditions, thus improving the health condition of the general public across the world.
这篇叙述性综述对人乳头瘤病毒(HPV)引起的皮肤病变进行了全面分析。人乳头瘤病毒是一种无处不在的病毒感染,可导致从良性疣状病变到恶性皮肤肿瘤等各种情况。鉴于全球人群感染率不断上升,本综述包括对HPV引起的皮肤表现的分析,以及持续采用成功的诊断技术和治疗方法的必要性。我们回顾了2000年至2023年期间所有135项与涉及皮肤的病理生理学、危险因素以及活检和分子检测等早期检测方法相关的研究。讨论了包括冷冻疗法和激光疗法在内的当前治疗方法,同时综述强调了HPV疫苗接种在预防感染方面的作用。未来的建议将包括加强公众教育、提高疫苗接种覆盖率,以及采用创新疗法以更好地管理或控制与人乳头瘤病毒(HPV)相关的皮肤疾病。通过推进这些建议,我们将更有能力预防和治疗HPV皮肤疾病,从而改善全球普通民众的健康状况。