Neacsu Andreea, Chihaia Viorel, Bucuresteanu Razvan, Ficai Anton, Trusca Roxana Doina, Surdu Vasile-Adrian, Nicolaev Adela, Cojocaru Bogdan, Ionita Monica, Calinescu Ioan, Parvulescu Viorica, Ditu Lia-Mara
Institute of Physical Chemistry "Ilie Murgulescu", Romanian Academy, Splaiul Independentei 202, 060021 Bucharest, Romania.
Microbiology Department, Faculty of Biology, University of Bucharest, Intr. Portocalelor 1-3, 060101 Bucharest, Romania.
Materials (Basel). 2024 Sep 12;17(18):4483. doi: 10.3390/ma17184483.
Ca- and Cu-decorated TiO microparticles are titanium dioxide nanoparticles that have been decorated with calcium and copper ions. TiO, CaO, and CuO are low-cost, non-toxic, and non-hazardous materials. The aim of the present study was the physicochemical characterization of Ca- and Cu-decorated TiO microparticles and the evaluation of their antimicrobial activity. Thus, Ca and Cu species were incorporated onto TiO surfaces by a two-step wet method. The obtained TiO-CaO-CuO composites were characterized by several experimental techniques. The electronic structure and charge properties of the composites were investigated by density functional theory calculations. Furthermore, the composites were successfully tested for inhibitory effects on , , , and standard strains. The zeta potential data indicate that the physiological condition of investigated microbial strains was strongly affected in presence of a dispersion of 10 μg/L of composites in a saline phosphate buffer also, the recorded SEM images show a damaged microbial cell surface in the presence of composites.
钙和铜修饰的二氧化钛微粒是用钙和铜离子修饰的二氧化钛纳米颗粒。二氧化钛、氧化钙和氧化铜是低成本、无毒且无害的材料。本研究的目的是对钙和铜修饰的二氧化钛微粒进行物理化学表征，并评估其抗菌活性。因此，通过两步湿法将钙和铜物种掺入二氧化钛表面。通过多种实验技术对所得的二氧化钛 - 氧化钙 - 氧化铜复合材料进行了表征。通过密度泛函理论计算研究了复合材料的电子结构和电荷性质。此外，成功测试了复合材料对标准菌株的抑制作用。zeta电位数据表明，在磷酸盐缓冲盐溶液中存在10μg/L复合材料分散体的情况下，所研究微生物菌株的生理状况受到强烈影响。记录的扫描电子显微镜图像也显示，在复合材料存在下微生物细胞表面受损。
