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局部释氧凝胶(bluem)对深牙周袋的影响:一例报告。

The Impact of a Topical Oxygen-Releasing Gel (bluem) on Deep Periodontal Pockets: A Case Report.

机构信息

Dental Health Department, College of Applied Medical Sciences, King Saud University, Riyadh 11433, Saudi Arabia.

Department of Periodontics and Community Dentistry, College of Dentistry, King Saud University, Riyadh 11433, Saudi Arabia.

出版信息

Medicina (Kaunas). 2024 Sep 19;60(9):1527. doi: 10.3390/medicina60091527.

DOI:10.3390/medicina60091527
PMID:39336568
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11434143/
Abstract

Periodontitis represents a prevalent oral pathological condition. Various supplementary local therapies are utilized in clinical practice. Recently introduced, topical oxygen therapy exhibits the potential to effectively hinder the growth of plaque (bacterial biofilm). Delivered in the form of an oral gel, this formulation contains cellulose, glycerol, and sodium peroxoborate, releasing topical oxygen in a regulated manner. Additionally, it discharges topical oxygen and lactoferrin in a controlled manner, with the former showcasing antibacterial properties and the latter stimulating bone cell activity. The primary objective of this particular case study is to present a scenario of periodontitis featuring deep periodontal pockets, which was effectively managed through clinical treatment with the use of adjunctive topical oxygen-releasing gel (bluem).

摘要

牙周炎是一种常见的口腔病理状况。在临床实践中,会使用各种辅助局部治疗。最近引入的局部氧气疗法具有有效抑制牙菌斑(细菌生物膜)生长的潜力。这种口腔凝胶形式的疗法含有纤维素、甘油和过硼酸钠,以受控的方式释放局部氧气。此外,它还以受控的方式释放局部氧气和乳铁蛋白,前者具有抗菌特性,后者刺激骨细胞活性。本案例研究的主要目的是介绍一个深牙周袋牙周炎的病例,通过使用辅助局部氧气释放凝胶(bluem)进行临床治疗,有效地对其进行了管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b53/11434143/8efd5266bba8/medicina-60-01527-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b53/11434143/e2cd7f6e6d91/medicina-60-01527-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b53/11434143/0d14899f9245/medicina-60-01527-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b53/11434143/8efd5266bba8/medicina-60-01527-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b53/11434143/e2cd7f6e6d91/medicina-60-01527-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b53/11434143/0d14899f9245/medicina-60-01527-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b53/11434143/8efd5266bba8/medicina-60-01527-g003.jpg

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本文引用的文献

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2
Association of active oxygen-releasing gel and photodynamic therapy in the treatment of residual periodontal pockets in type 2 diabetic patients: A randomized controlled clinical study.活性氧凝胶联合光动力疗法治疗 2 型糖尿病患者牙周袋残余的随机对照临床研究。
J Periodontol. 2024 Apr;95(4):360-371. doi: 10.1002/JPER.23-0125. Epub 2023 Dec 19.
3
A Narrative Review on Means to Promote Oxygenation and Angiogenesis in Oral Wound Healing.
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Bioengineering (Basel). 2022 Nov 2;9(11):636. doi: 10.3390/bioengineering9110636.
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Dynamic Role of Oxygen in Wound Healing: A Microbial, Immunological, and Biochemical Perspective.动态氧在伤口愈合中的作用:微生物学、免疫学和生物化学视角。
Arch Razi Inst. 2022 Apr 30;77(2):513-523. doi: 10.22092/ARI.2022.357230.2003. eCollection 2022 Apr.
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Global, regional, and national burden of severe periodontitis, 1990-2019: An analysis of the Global Burden of Disease Study 2019.全球、地区和国家严重牙周炎负担,1990-2019 年:基于 2019 年全球疾病负担研究的分析。
J Clin Periodontol. 2021 Sep;48(9):1165-1188. doi: 10.1111/jcpe.13506. Epub 2021 Jul 7.
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Effects of Active Oxygen Toothpaste in Supragingival Biofilm Reduction: A Randomized Controlled Clinical Trial.活性氧牙膏对减少龈上生物膜的效果:一项随机对照临床试验。
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