Saeidi Abdullah, Gülses Aydin, Jamil Maryam, Alolayan Albraa, Elsayed Shadia, Wiltfang Jörg, Flörke Christian
Department of Oral and Maxillofacial Diagnostic Sciences, College of Dentistry, Taibah University, Madinah 42353, Saudi Arabia.
Department of Oral and Maxillofacial Surgery, University Medical Center Schleswig-Holstein, Campus Kiel, 24118 Kiel, Germany.
J Clin Med. 2024 Sep 14;13(18):5470. doi: 10.3390/jcm13185470.
: Basal cell carcinoma is the most common nonmelanoma skin cancer, followed by cutaneous squamous cell carcinoma. The objective of the current study was to retrospectively evaluate the epidemiology, characteristic variations, histological aspects, and prognosis of basal cell carcinoma of the facial region based on a single-centre experience. : Data from 125 patients admitted to the Department of Oral and Maxillofacial Surgery, University Medical Center Schleswig-Holstein (UKSH), Kiel, for surgical treatment of basal cell carcinomas of the face between January 2015 and April 2021 were evaluated. : The mean patient age was 79.58 years, 60.5% were male and 39.5% were female. Six patients (4.8%) had tumour recurrence with no regional metastasis. Seventy-nine patients (63%) were classified as T1. The nose and the temporal region were the most common areas. The mean tumour thickness was 3.20 mm. : Micronodular, sclerosing/morphoeic, nodular, and superficial growth patterns of basal cell carcinoma are highly correlated to recurrence, so an excision safety margin is recommended. There is a strong correlation between tumour thickness and recurrence among basal cell carcinoma cases. When completely excised, the recurrence rate for basal cell carcinoma is relatively low.
基底细胞癌是最常见的非黑色素瘤皮肤癌,其次是皮肤鳞状细胞癌。本研究的目的是基于单中心经验,回顾性评估面部基底细胞癌的流行病学、特征变异、组织学特征和预后。
对2015年1月至2021年4月期间因面部基底细胞癌接受手术治疗而入住基尔大学石勒苏益格-荷尔斯泰因大学医学中心(UKSH)口腔颌面外科的125例患者的数据进行了评估。
患者的平均年龄为79.58岁,男性占60.5%,女性占39.5%。6例患者(4.8%)出现肿瘤复发,无区域转移。79例患者(63%)被归类为T1期。鼻子和颞部是最常见的部位。肿瘤的平均厚度为3.20毫米。
基底细胞癌的微结节型、硬化/硬斑病样型、结节型和浅表型生长模式与复发高度相关,因此建议有安全切缘。在基底细胞癌病例中,肿瘤厚度与复发之间存在很强的相关性。当完全切除时,基底细胞癌的复发率相对较低。