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颈椎立体定向放射治疗中HyperArc与传统容积调强弧形放疗的剂量学比较

Dosimetric Comparison between the HyperArc and Conventional VMAT in Cervical Spine Stereotactic Radiosurgery.

作者信息

Park Jeehoon, Park Byungdo, Kim Jeongho

机构信息

Department of Radiation Oncology, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon 630-522, Republic of Korea.

出版信息

J Clin Med. 2024 Sep 17;13(18):5497. doi: 10.3390/jcm13185497.

Abstract

This research aims to evaluate the usability of the HyperArc (HA) technique in stereotactic radiosurgery for cervical spine metastasis by comparing the dosimetry of the target and organs at risk, specifically the spinal cord, between HA and VMAT and conventional volumetric modulated arc therapy (VMAT). A RANDO phantom and QFix Encompass and support system were used to simulate three target types (A, B, and C) based on RTOG0631 guidelines. Treatment plans included one VMAT and two HyperArc techniques with different SRS NTO values (100 and 250). Dosimetric parameters such as conformity index (CI), homogeneity index (HI), R, and spinal cord sparing were analyzed. Gamma analysis was performed using portal dosimetry to validate the dose delivery accuracy. HyperArc plans demonstrated higher conformity, sharper dose fall-off, and improved quality assurance (QA) results compared to VMAT plans. HA with SRS NTO 250 showed even better results in terms of conformity, dose fall-off, and spinal cord dose reduction (V and D) compared to HA with SRS NTO 100. Although the mean gamma passing rates were slightly lower, all plans achieved rates above 95%. The findings suggest that HA provides superior dosimetric benefits over VMAT and could be effectively utilized for cervical spine radiation therapy.

摘要

本研究旨在通过比较在立体定向放射治疗颈椎转移瘤中,HyperArc(HA)技术与容积调强弧形放疗(VMAT)和传统容积调强弧形放疗中靶区和危及器官(特别是脊髓)的剂量学,来评估HA技术的可用性。使用RANDO体模以及QFix Encompass和支撑系统,根据RTOG0631指南模拟三种靶区类型(A、B和C)。治疗计划包括一个VMAT计划和两种具有不同立体定向放射治疗非靶区(SRS NTO)值(100和250)的HyperArc技术。分析了适形指数(CI)、均匀性指数(HI)、R和脊髓保护等剂量学参数。使用射野剂量学进行伽马分析,以验证剂量传递准确性。与VMAT计划相比,HyperArc计划显示出更高的适形性、更陡峭的剂量下降以及更好的质量保证(QA)结果。与SRS NTO为100的HA相比,SRS NTO为250的HA在适形性、剂量下降和脊髓剂量降低(V和D)方面表现出更好的结果。尽管平均伽马通过率略低,但所有计划的通过率均高于95%。研究结果表明,HA在剂量学方面优于VMAT,可有效用于颈椎放射治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4917/11432059/6a14f0444d96/jcm-13-05497-g001.jpg

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