Wollner Gregor, Hruska Florian, Koenig Felix R M, Haider Thomas, Negrin Lukas L
Department of Orthopedics and Trauma-Surgery, Medical University of Vienna, 1090 Vienna, Austria.
Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, 1090 Vienna, Austria.
J Clin Med. 2024 Sep 19;13(18):5557. doi: 10.3390/jcm13185557.
Heterotopic ossifications (HOs) are a well-known complication following total hip arthroplasty. Yet only little is known about the development of HOs following a femoral fracture and intramedullary stabilization in polytraumatized patients. Thus, the present study aimed to investigate whether the development of HOs is being observed more frequently in patients suffering polytrauma compared to those with single-extremity trauma.
The retrospective outcome study was conducted at our level I trauma center. All patients admitted from 2010 to 2020 were included if they (1) presented with multiple injuries (≥2 body regions), (2) had an Injury Severity Score ≥16, (3) suffered a femoral fracture, and (4) were treated with intramedullary stabilization. Furthermore, a control group was established to match the polytrauma group (sex, age), who were suffering from single-extremity trauma (femoral fracture) which was treated with intramedullary stabilization. Subsequently, X-rays of the hip were performed and evaluated for up to one-year post-trauma.
Our study group consisted of 36 patients in total (91.7% male; mean age 39.4 ± 17.4 years, range: 18-82 years). The polytrauma (PT) group included 12 patients (mean age 39.5 years, median ISS 28), whereas the control group (single-extremity-trauma) included 24 patients (mean age 39.3 years). We documented HOs in nine (75%) patients in the PT group vs. five (20.8%) patients in the single-extremity group ( = 0.03).
In this study, we were able to demonstrate that heterotopic ossifications are being observed significantly more frequently in patients suffering from polytrauma in comparison to patients with single-extremity trauma following intramedullary stabilization after a femoral fracture.
异位骨化（HOs）是全髋关节置换术后一种众所周知的并发症。然而，对于多发伤患者股骨骨折及髓内固定术后HOs的发生情况却知之甚少。因此，本研究旨在调查与单肢创伤患者相比，多发伤患者中HOs的发生是否更常见。
本回顾性结局研究在我们的一级创伤中心进行。纳入2010年至2020年期间收治的所有患者，条件为：（1）存在多发伤（≥2个身体部位）；（2）损伤严重程度评分≥16；（3）发生股骨骨折；（4）接受髓内固定治疗。此外，设立一个对照组，与多发伤组（性别、年龄）匹配，对照组为接受髓内固定治疗的单肢创伤（股骨骨折）患者。随后，在创伤后长达一年的时间内对髋关节进行X线检查并评估。
我们的研究组共有36例患者（男性占91.7%；平均年龄39.4±17.4岁，范围：18 - 82岁）。多发伤（PT）组包括12例患者（平均年龄39.5岁，ISS中位数28），而对照组（单肢创伤）包括24例患者（平均年龄39.3岁）。我们记录到PT组9例（75%）患者出现HOs，而单肢创伤组有5例（20.8%）患者出现HOs（P = 0.03）。
在本研究中，我们能够证明，与股骨骨折髓内固定术后的单肢创伤患者相比，多发伤患者中异位骨化的发生率明显更高。
