Yazdani Ariella, Sweterlitsch Katherine Moran, Kim Hanna, Flyckt Rebecca L, Christianson Mindy S
Cleveland Clinic Foundation, Cleveland, OH 44195, USA.
Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
J Clin Med. 2024 Sep 20;13(18):5577. doi: 10.3390/jcm13185577.
As oncologic therapy continues to advance, survivorship care has widened the realm of possibilities for quality-of-life improvements, including fertility preservation and restoration. We aim to summarize the current and future directions of fertility preservation techniques for patients facing gonadotoxic medical therapies who desire pregnancy after their condition is treated. This review of both ovarian and uterine transposition highlights the present roles, techniques, and fertility outcomes of the two fertility preservation treatment modalities designed to protect reproductive organs from harmful pelvic radiation. Current evidence shows that ovarian transposition preserves ovarian function for patients with localized pelvic radiation demonstrating the most successful return of fertility. Uterine transposition holds great promise for patients desiring to conceive and carry a full-term pregnancy after radiation therapy. With ongoing advancements in oncologic treatments leading to increased survival rates, fertility is increasingly becoming a key survivorship issue. Patients can anticipate counseling about these fertility preservation surgical techniques that protect both the ovaries as well as the uterus from harmful pelvic radiation.
随着肿瘤治疗的不断进步，生存护理拓宽了改善生活质量的可能性领域，包括生育力保存和恢复。我们旨在总结对于接受性腺毒性药物治疗且希望在病情得到治疗后怀孕的患者，生育力保存技术的当前及未来发展方向。这篇关于卵巢和子宫移位术的综述强调了两种生育力保存治疗方式目前的作用、技术及生育结局，这两种方式旨在保护生殖器官免受盆腔有害辐射。目前的证据表明，对于接受局部盆腔放疗的患者，卵巢移位术可保留卵巢功能，生育力恢复最为成功。子宫移位术对于放疗后希望受孕并足月妊娠的患者具有很大的前景。随着肿瘤治疗的不断进步，生存率不断提高，生育力日益成为生存护理的关键问题。患者可以期待接受关于这些生育力保存手术技术的咨询，这些技术可保护卵巢和子宫免受盆腔有害辐射。
