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病例报告:类风湿性关节炎患者合并髋关节感染及髋臼突出行全髋关节置换术:病例研究与文献综述

Case Report: Rheumatoid arthritis patient with hip joint infection and acetabular protrusion undergoing total hip arthroplasty: a case study and literature review.

作者信息

Zhou Jun, Zhou Weijie, Wang Peng, Zhang Yinwei, Chu Weitao, Fan Jun, Lu Hui

机构信息

Department of Orthopedics, Jinyun People's Hospital, Lishui, Zhejiang, China.

Department of Orthopedics, No. 903 Hospital of PLA Joint Logistic Support Force, Hangzhou, Zhejiang, China.

出版信息

Front Surg. 2025 Mar 18;12:1534279. doi: 10.3389/fsurg.2025.1534279. eCollection 2025.

Abstract

The chronic autoimmune disease rheumatoid arthritis (RA) affects primarily the synovial joints, leading to hip joint deformity and dysfunction manifestations such as acetabular protrusion and joint infection. We present the case of a female patient RA complicated by severe hip arthritis and acetabular protrusion syndrome. The disease progressed rapidly with elevated preoperative inflammatory markers, initially overlooking hip joint infection. The patient underwent total hip arthroplasty, and intraoperative synovial fluid bacterial culture revealed Gram-negative rod bacteria. Aggressive postoperative anti-infective therapy effectively controlled the infection. Therefore, early diagnosis and treatment of infections are particularly important.

摘要

慢性自身免疫性疾病类风湿关节炎(RA)主要影响滑膜关节,导致髋关节畸形和功能障碍,如髋臼突出和关节感染等表现。我们报告了一例类风湿关节炎女性患者并发严重髋关节炎和髋臼突出综合征的病例。该疾病进展迅速,术前炎症标志物升高,最初忽略了髋关节感染。患者接受了全髋关节置换术,术中滑膜液细菌培养显示为革兰氏阴性杆菌。积极的术后抗感染治疗有效控制了感染。因此,感染的早期诊断和治疗尤为重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a46/11958972/3b7ff91a6fe5/fsurg-12-1534279-g001.jpg

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