Pereira Catarina Ramos, Greten Henry J, Santos Rubim, Reis Ana Mafalda, Ramos Bruno, Santos Maria João, Machado Jorge, Criado Maria Begoña
ICBAS-Abel Salazar Institute for Biomedical Sciences, University of Porto, 4099-002 Porto, Portugal.
Piaget Institute, Vila Nova de Gaia, 4099-002 Porto, Portugal.
J Clin Med. 2024 Sep 23;13(18):5642. doi: 10.3390/jcm13185642.
Parkinson's Disease (PD) is a progressive neurodegenerative condition associated with deficit in reaction time which can lead to falls, resulting in limited independence, diminished quality of life, heightened rates of institutionalization and increased healthcare costs. We aimed to examine the effects of an acupuncture protocol in motor time response after an auditory stimulus. : This study employed a case series design. Reaction time to exposed rhythmic and random auditory stimuli outcomes were evaluated at six different moments over a month-long acupuncture treatment protocol using the MP 36 system from Biopac Systems. : We observed a tendency to have more pronounced improvements in the time response in the more affected side of the body compared with the contralateral one. Patients tended to show better values of response to random auditory stimuli compared to rhythmic auditory ones. We also observed a tendency to obtain better results when considering the accumulative effects of the acupuncture protocol. : Our findings indicated a possible role of reaction time as a sensitive and useful tool for motor function assessment in PD patients. Also, from our results, we concluded that the acupuncture protocol used may lead to an improvement in efficacy of motor response after aleatory and rhythmic stimulus; we also found a tendency for a higher efficacy of acupuncture in random stimuli responses in the first stages of the disease. However, further in-depth research, including a statistical evaluation with a larger participant pool, is necessary to validate and confirm these promising results.
帕金森病（PD）是一种进行性神经退行性疾病，与反应时间缺陷有关，这可能导致跌倒，从而导致独立性受限、生活质量下降、机构化率升高和医疗成本增加。我们旨在研究针刺方案对听觉刺激后运动时间反应的影响。：本研究采用病例系列设计。在为期一个月的针刺治疗方案中，使用来自Biopac Systems的MP 36系统，在六个不同时间点评估对暴露的有节奏和随机听觉刺激结果的反应时间。：我们观察到，与对侧相比，身体受影响更严重一侧的时间反应改善更为明显。与有节奏的听觉刺激相比，患者对随机听觉刺激的反应值往往更好。当考虑针刺方案的累积效应时，我们还观察到获得更好结果的趋势。：我们的研究结果表明，反应时间可能作为评估PD患者运动功能的一种敏感且有用的工具。此外，从我们的结果来看，我们得出结论，所使用的针刺方案可能会提高随机和有节奏刺激后运动反应的疗效；我们还发现，在疾病的第一阶段，针刺对随机刺激反应的疗效有更高的趋势。然而，需要进一步深入研究，包括对更大样本量进行统计评估，以验证和确认这些有前景的结果。
