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身体冷暴露(冷冻溶脂)对脂肪量和血浆胆固醇的影响。

The Effects of Body Cold Exposure (Cryolipolysis) on Fat Mass and Plasma Cholesterol.

作者信息

Lopes-Martins Rodrigo Alvaro Brandão, Barbosa Ludymilla Vicente, Sousa Mirian Martins Barbosa, Lobo Anna Beatriz, Santos Elize Leonice da Rocha, Sá Filho Alberto Souza de, Souza Matheus Bernardes, Jaime Jivago Carneiro, Silva Constanza Thaise Xavier da, Ruiz-Silva Carlos, Leonardo Patrícia Sardinha

机构信息

Laboratory of Biophotonics and Experimental Therapeutics (LABITEX), Universidade Evangélica de Goiás, Av. Universitária Km 3,5, Anápolis 75083-515, Brazil.

Programa de Pós-Graduação em Bioengenharia, Universidade Brasil, Av. Carolina Fonseca 236, Itaquera, São Paulo 08230-030, Brazil.

出版信息

Life (Basel). 2024 Aug 29;14(9):1082. doi: 10.3390/life14091082.

Abstract

INTRODUCTION

This study investigates the impact of cryolipolysis on reducing localized fat and altering plasma lipid profiles in 30 overweight and obese women. Conducted at the Health Technology Laboratory of the Evangelical University of Goiás, this clinical research adhered to stringent ethical guidelines.

METHODS

Participants underwent three cryolipolysis sessions, with comprehensive assessments of body composition and plasma lipids performed pre- and post-intervention.

RESULTS

Significant findings include a reduction in abdominal fat mass by an average of 4.1 kg and a decrease in BMI by 0.7 points ( < 0.05). Notably, total cholesterol levels decreased by an average of 15.7 mg/dL, and LDL cholesterol saw a reduction of 10.2 mg/dL ( < 0.01), with no significant changes in HDL cholesterol or triglyceride levels. These results suggest that cryolipolysis, in conjunction with standardized dietary control, offers a non-invasive alternative to surgical fat reduction, potentially mitigating cardiovascular risks associated with obesity.

CONCLUSIONS

The study confirms the efficacy of cryolipolysis in targeted fat reduction and underscores its role in improving key cardiovascular risk factors. These findings warrant further exploration into the long-term benefits of cryolipolysis in metabolic health management and not only for aesthetic treatments.

摘要

引言

本研究调查了冷冻溶脂术对30名超重和肥胖女性减少局部脂肪及改变血脂谱的影响。这项临床研究在戈亚斯福音大学健康技术实验室进行,遵循了严格的伦理准则。

方法

参与者接受了三次冷冻溶脂治疗,并在干预前后对身体成分和血脂进行了全面评估。

结果

显著发现包括腹部脂肪量平均减少4.1千克,体重指数降低0.7点(<0.05)。值得注意的是,总胆固醇水平平均下降15.7毫克/分升,低密度脂蛋白胆固醇下降10.2毫克/分升(<0.01),而高密度脂蛋白胆固醇或甘油三酯水平无显著变化。这些结果表明,冷冻溶脂术结合标准化饮食控制,为手术减脂提供了一种非侵入性替代方法,可能降低与肥胖相关的心血管风险。

结论

该研究证实了冷冻溶脂术在针对性减脂方面的有效性,并强调了其在改善关键心血管危险因素方面的作用。这些发现值得进一步探索冷冻溶脂术在代谢健康管理中的长期益处,而不仅仅是用于美容治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca45/11433038/efe693f2c46d/life-14-01082-g001.jpg

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