Department of Biochemistry, College of Medicine and Health Sciences, National University of Science and Technology, Al Tareef, Sohar 321, Oman.
College of Medicine and Health Sciences, National University of Science and Technology, Al Tareef, Sohar 321, Oman.
Int J Environ Res Public Health. 2024 Sep 2;21(9):1165. doi: 10.3390/ijerph21091165.
PCOS, a common hormonal disorder in women of reproductive age, affects fertility and increases the risks of other diseases. Early detection, risk factor assessment, and intervention are crucial to prevent long-term complications.
This study was conducted using a pre-validated questionnaire at two medical colleges in the UAE and Oman. The first study (UAE) results are already published. Here, we present the findings of the second study (Oman) and compare them.
The prevalence of PCOS was 4.6% ( = 7) in Oman and 27.6% ( = 69) in the UAE using the NIH criteria. The most common symptoms were irregular periods, acne, and thinning of hair. Students showed acne as the most prevalent symptom of clinical hyperandrogenism. Omani students showed significantly more acne [70.1% ( = 108) vs. 41.6% ( = 104)], while Emirati students showed a higher prevalence of hirsutism [32% ( = 80) vs. 23.3% ( = 36)]. A higher number of students had irregular periods 30.8% (77/150) in the UAE, although the difference was not statistically significant. The prevalence of PCOS was significantly higher in Emirati medical students than in Omani students ( < 0.05). The prevalence was also lower among medical students in Oman compared to an unselected population, reported by a study that included all consecutive women between 12 and 45 years of age attending a hospital. An increased trend in unhealthy lifestyle practices was observed in the recent study. Obesity was a strong predictor of PCOS symptoms across the populations in both countries ( < 0.05).
The prevalence of PCOS and clinical signs of hyperandrogenism vary significantly between countries in the MENA region. There is a need to identify specific risk factors associated with PCOS in different populations, explore the genetic basis, and undertake collaborative efforts among healthcare professionals from various disciplines to raise awareness about PCOS and its associated risks.
多囊卵巢综合征（PCOS）是育龄妇女常见的激素紊乱疾病，会影响生育能力并增加其他疾病的风险。早期发现、评估风险因素和干预至关重要，可以预防长期并发症。
本研究在阿联酋和阿曼的两所医学院使用预先验证的问卷进行。第一项研究（阿联酋）的结果已经发表。在这里，我们展示第二项研究（阿曼）的结果并进行比较。
使用 NIH 标准，阿曼的 PCOS 患病率为 4.6%（=7），阿联酋为 27.6%（=69）。最常见的症状是月经不规律、痤疮和头发稀疏。学生表现出痤疮是最常见的临床高雄激素症状。阿曼学生的痤疮发生率明显更高[70.1%（=108）比 41.6%（=104）]，而阿联酋学生的多毛症发生率更高[32%（=80）比 23.3%（=36）]。阿联酋有更多的学生出现月经不规律 30.8%（77/150），尽管差异无统计学意义。阿联酋医学生的 PCOS 患病率明显高于阿曼学生（<0.05）。与一项包括所有 12 至 45 岁连续就诊医院的女性的未选择人群的研究相比，阿曼医学生的 PCOS 患病率也较低。在最近的研究中观察到不健康生活方式的流行趋势增加。肥胖是两国人群 PCOS 症状的强烈预测因素（<0.05）。
中东和北非地区各国的 PCOS 患病率和高雄激素临床体征存在显著差异。需要确定不同人群中与 PCOS 相关的特定风险因素，探索遗传基础，并开展来自不同学科的医疗保健专业人员之间的合作，提高对 PCOS 及其相关风险的认识。
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