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妊娠相关血栓栓塞——急诊科当前面临的挑战

Pregnancy-Related Thromboembolism-Current Challenges at the Emergency Department.

作者信息

Moroi Ștefan-Ionuț, Weiss Emma, Stanciu Silviu, Bădilă Elisabeta, Ilieșiu Adriana Mihaela, Balahura Ana-Maria

机构信息

Department of Cardiology, Emergency Institute for Cardiovascular Diseases "Prof. Dr. C.C. Iliescu", 022328 Bucharest, Romania.

"Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.

出版信息

J Pers Med. 2024 Aug 31;14(9):926. doi: 10.3390/jpm14090926.

Abstract

Thrombotic events during pregnancy are burdened by an increased risk of morbidity and mortality, despite innovations in their diagnosis and treatment. Given their multifactorial etiology, it is important to understand all the pathophysiological mechanisms but especially to achieve correct and timely diagnosis. Pulmonary embolism (PE) during pregnancy represents a rare event, with an incidence of 1 per 1000 pregnancies, but it is also one of the leading causes of death during pregnancy. Managing PE in the acute setting is even more challenging and complex due to the attempt to maintain a balance between hemorrhagic and thrombotic complications while ensuring an optimal outcome for both the mother and the baby. In this review, our aim is to analyze the most significant challenges of acute PE during pregnancy and identify suitable management approaches for specific situations in order to improve the prognosis of pregnant women.

摘要

尽管在血栓形成事件的诊断和治疗方面有所创新,但孕期血栓形成事件的发病和死亡风险仍有所增加。鉴于其多因素病因,了解所有病理生理机制很重要,但尤其要实现正确和及时的诊断。孕期肺栓塞(PE)是一种罕见事件,发生率为每1000次妊娠中有1例,但它也是孕期死亡的主要原因之一。由于要在出血和血栓形成并发症之间保持平衡,同时确保母婴获得最佳结局,因此在急性情况下管理PE更具挑战性和复杂性。在本综述中,我们的目的是分析孕期急性PE的最重大挑战,并确定针对特定情况的合适管理方法,以改善孕妇的预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9be7/11433414/765513d343e5/jpm-14-00926-g001.jpg

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