Bessegatto José Antônio, Lisbôa Júlio Augusto Naylor, Martins Felippe Danyel Cardoso, Freire Roberta Lemos, Facury Filho Elias Jorge, Alfieri Amauri Alcindo, Costa Marcio C
Department of Clinical Sciences and Preventive Veterinary Medicine, Universidade Estadual de Londrina, Rodovia Celso Garcia Cid (PR 445) Km 380, Londrina 86057-970, PR, Brazil.
Department of Veterinary Medicine and Surgery, Universidade Federal de Minas Gerais-UFMG, Av. Antônio Carlos 6627, Belo Horizonte 31270-901, MG, Brazil.
Microorganisms. 2024 Aug 23;12(9):1744. doi: 10.3390/microorganisms12091744.
spp. is one of the most important pathogens infecting nursing calves worldwide. This study aimed to investigate the intestinal microbiota of dairy calves during the first month of life and the impact of diarrhea caused by on a Brazilian farm. Fecal samples from 30 calves were collected during the first month of life, and fecal scores were recorded. Samples from the second, third, and fourth days of life were analyzed by DNA sequencing of the 16S rRNA gene. In addition, samples of sixteen calves positive for spp. were retrospectively chosen according to the development of diarrhea: four and two days before diarrhea, at the onset of diarrhea, after four days of diarrhea, at the end of diarrhea, and after six days of diarrhea resolution. Diarrhea was observed in all calves (100%), starting at day 5 of life, and all calves tested positive for in at least one sample. The microbiota richness increased with age but was retarded by diarrhea. Compositional changes associated with infection included increases in , and , as well as decreases in and Lachnospiraceae. In conclusion, infection has the potential to decrease richness and change the composition of the intestinal microbiota of dairy calves.
某菌属是全球范围内感染哺乳犊牛的最重要病原体之一。本研究旨在调查巴西某农场犊牛出生后第一个月的肠道微生物群，以及由该菌属引起的腹泻的影响。在犊牛出生后的第一个月收集了30头犊牛的粪便样本，并记录粪便评分。对出生后第二、第三和第四天的样本进行16S rRNA基因的DNA测序分析。此外，根据腹泻的发展情况，回顾性选择了16头某菌属检测呈阳性的犊牛的样本：腹泻前四天和两天、腹泻发作时、腹泻四天后、腹泻结束时以及腹泻缓解六天后。所有犊牛（100%）均出现腹泻，始于出生后第5天，且所有犊牛至少有一个样本某菌属检测呈阳性。微生物群丰富度随年龄增长，但因腹泻而受到抑制。与该菌属感染相关的组成变化包括某菌属、某菌属和某菌属增加，以及某菌属和毛螺菌科减少。总之，该菌属感染有可能降低丰富度并改变犊牛肠道微生物群的组成。
Zotero 插件
