Qiu Yuan, Lau Lawrence, Khan Zaim, Messika-Zeitoun David, Ruel Marc, Chan Vincent
Division of Cardiac Surgery, University of Ottawa Heart Institute, Ottawa, ON K1Y 4W7, Canada.
Division of Cardiology, University of Ottawa Heart Institute, Ottawa, ON K1Y 4W7, Canada.
Microorganisms. 2024 Sep 1;12(9):1809. doi: 10.3390/microorganisms12091809.
Mitral valve repair is the ideal approach in managing mitral valve infective endocarditis for patients requiring surgery. However, viable repair is influenced by the extent of valve destruction and there can be technical challenges in reconstruction following debridement. Overall, data describing long-term outcomes following mitral repair of infective endocarditis are scarce. We, therefore, assessed the late outcomes of 101 consecutive patients who underwent mitral valve repair for IE at the University of Ottawa Heart Institute from 2001 to 2021. The 5- and 10-year survival rate was 80.8 ± 4.7% and 61.2 ± 9.2%, respectively. Among these 101 patients, 7 ultimately required mitral valve reoperation at a median of 5 years after their initial operation. These patients were of a mean age of 35.9 ± 7.3 years (range 22-44 years) at the time of their initial operation. The 5- and 10-year freedom from mitral valve reoperation was 93.6 ± 3.4% and 87.7 ± 5.2%, respectively. Overall, mitral valve repair can be an effective method for treating infective endocarditis with a favourable freedom from reoperation and mortality over the long term.
对于需要手术的二尖瓣感染性心内膜炎患者，二尖瓣修复是理想的治疗方法。然而，可行的修复受到瓣膜破坏程度的影响，清创后重建可能存在技术挑战。总体而言，描述二尖瓣感染性心内膜炎修复术后长期结局的数据较少。因此，我们评估了2001年至2021年在渥太华大学心脏研究所接受二尖瓣修复治疗感染性心内膜炎的101例连续患者的晚期结局。5年和10年生存率分别为80.8±4.7%和61.2±9.2%。在这101例患者中，7例最终在初次手术后中位5年需要再次进行二尖瓣手术。这些患者初次手术时的平均年龄为35.9±7.3岁（范围22 - 44岁）。二尖瓣再次手术的5年和10年无再手术率分别为93.6±3.4%和87.7±5.2%。总体而言，二尖瓣修复可以是治疗感染性心内膜炎的有效方法，长期来看再手术率和死亡率较低。
