Silva Víctor, Silva Ceidy, Silva Coral, Gacitúa Rodrigo, Salas Hernán, Guzmán Neftalí, Alburquenque Claudio, Silva-Abello Viviana
VSV-Consulting-LATAM, Pucón 4920000, Chile.
Unidad de Medicina, Hospital Santo Tomas de Limache, Valparaíso 2240421, Chile.
Microorganisms. 2024 Sep 19;12(9):1907. doi: 10.3390/microorganisms12091907.
We studied yeast hand carriage of 260 healthcare students. We isolated yeasts in 27 students (10.4%), without differences between medicine, nursing, and medical laboratory science programs and gender. A significant lower prevalence of carriage was shown in the clinical cycle (2.7%) compared to the basic cycle (13.5%) ( = 0.022) and the preclinical cycle (13.5%) ( = 0.014). Increased handwashing frequency and the use of alcohol gel and antiseptic soap decreased yeast carriage. Students who applied moisturizing hand cream two or more times a day had a lower frequency of yeast carriage (3.4%) than those who did not use it or used it once a day (16.5%), showing a significant difference ( = 0.016). The most prevalent species was (81.5%), followed by () (7.4%), (7.4%), and (3.7%). One case showed mixed carriage of and . All strains were sensitive to voriconazole, caspofungin, and anidulafungin. This study shows hand carriage of yeast in health students, mainly by , and the frequency of infection control measures and moisturizing hand cream is associated with colonization control.
我们对260名医护专业学生的手部酵母菌携带情况进行了研究。我们在27名学生（10.4%）中分离出了酵母菌，医学、护理和医学检验专业以及不同性别之间并无差异。与基础阶段（13.5%）（P = 0.022）和临床前阶段（13.5%）（P = 0.014）相比，临床阶段的酵母菌携带率显著更低（2.7%）。增加洗手频率以及使用酒精凝胶和抗菌肥皂可降低酵母菌携带率。每天使用保湿护手霜两次或更多次的学生，其酵母菌携带率（3.4%）低于未使用或每天仅使用一次的学生（16.5%），差异具有统计学意义（P = 0.016）。最常见的菌种是近平滑假丝酵母菌（81.5%），其次是热带假丝酵母菌（7.4%）、克柔假丝酵母菌（7.4%）和光滑假丝酵母菌（3.7%）。1例显示近平滑假丝酵母菌和热带假丝酵母菌混合携带。所有菌株对伏立康唑、卡泊芬净和阿尼芬净均敏感。本研究表明，健康学生手部存在酵母菌携带情况，主要是近平滑假丝酵母菌，并且感染控制措施和保湿护手霜的使用频率与定植控制相关。
