AlRawashdeh Mousa M, Ishak Angela, Al-Bunnia Ahmed, Agouridis Aris P, Lytras Theodore, Spernovasilis Nikolaos, Tsioutis Constantinos
School of Medicine, European University Cyprus, 2404 Nicosia, Cyprus.
Department of Internal Medicine, Henry Ford Health System, Detroit, MI 48202, USA.
Pathogens. 2024 Sep 22;13(9):817. doi: 10.3390/pathogens13090817.
Infections by multidrug-resistant organisms (MDROs) pose significant public health challenges, including increased mortality rates, healthcare costs, and significant impacts on the quality of life for patients. Utilizing a systematic review methodology adhering to PRISMA guidelines, we performed a comprehensive search across three databases, identifying 20 relevant studies that investigated the psychological effects of infections due to MDROs on hospitalized adults. The primary outcomes examined included depression, anxiety, and other psychosocial impacts, while secondary outcomes included patient and caregiver understanding of the infection. Findings revealed consistent associations between contact isolation due to MDRO infections and heightened levels of depression and anxiety among patients, although evidence regarding the impact on anger was mixed. Other psychological aspects, such as feelings of stigmatization and reduced healthcare provider interactions, were also recorded. The current systematic review highlights the importance of addressing these psychological effects through holistic, patient-centered care approaches, emphasizing the need for better communication and comprehensive education for both patients and healthcare providers. Our findings suggest that mitigating the psychological burden of MDROs can enhance overall patient care and outcomes and call for further research to optimize care strategies for patients hospitalized for infections due to MDROs.
多重耐药菌（MDROs）感染带来了重大的公共卫生挑战，包括死亡率上升、医疗成本增加以及对患者生活质量产生重大影响。我们采用遵循PRISMA指南的系统评价方法，在三个数据库中进行了全面检索，确定了20项相关研究，这些研究调查了MDROs感染对住院成人的心理影响。所考察的主要结局包括抑郁、焦虑和其他社会心理影响，次要结局包括患者和护理人员对感染的理解。研究结果显示，MDROs感染导致的接触隔离与患者抑郁和焦虑水平升高之间存在一致的关联，尽管关于对愤怒影响的证据不一。还记录了其他心理方面，如被污名化的感觉和与医护人员互动减少。当前的系统评价强调了通过全面的、以患者为中心的护理方法来应对这些心理影响的重要性，强调了对患者和医护人员进行更好沟通和全面教育的必要性。我们的研究结果表明，减轻MDROs带来的心理负担可以改善整体患者护理和结局，并呼吁进一步开展研究以优化因MDROs感染而住院患者的护理策略。
