Acikgoz Orhan, Abelt Christopher
Department of Chemistry, College of William and Mary, Williamsburg, VA 23185, USA.
Molecules. 2024 Sep 12;29(18):4330. doi: 10.3390/molecules29184330.
Dynamic range is a crucial aspect in the development of fluorescent chemosensors. We aimed to address this issue using molecular logic gates. By creating an AND logic gate with two binding sites for the same type of ion, we increased the dynamic range of a sodium chemosensor while still using the same ionophore. Naphthalimide derivatives and were synthesized to test the plausibility of this application. Being an AND logic gate, the second molecule requires two Na ions, while molecule requires a single ion for sensing. The application of this molecular logic gate is a useful method of altering the chemosensor range.
动态范围是荧光化学传感器开发中的一个关键方面。我们旨在使用分子逻辑门来解决这个问题。通过创建一个具有两个针对同类型离子的结合位点的与逻辑门，我们在仍使用相同离子载体的情况下增加了钠化学传感器的动态范围。合成了萘酰亚胺衍生物 和 以测试该应用的可行性。作为一个与逻辑门，第二个分子需要两个钠离子，而分子 需要单个离子来进行传感。这种分子逻辑门的应用是改变化学传感器范围的一种有用方法。
