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scToppR:ToppGene 的编码友好型 R 接口。

scToppR: a coding-friendly R interface to ToppGene.

机构信息

Bioinformatics Core, Department of Neuroscience, Medical University of South Carolina, Charleston, SC 29425, United States.

Neurogenomics Laboratory, Department of Neuroscience, Medical University of South Carolina, Charleston, SC 29425, United States.

出版信息

Bioinformatics. 2024 Nov 1;40(11). doi: 10.1093/bioinformatics/btae582.

Abstract

MOTIVATION

The scToppR package provides a ToppGene interface from R programs/scripts to fully access/control the database for functional enrichment without the need for active interaction on its Web site (https://toppgene.cchmc.org/).

RESULTS

The library facilitates the functional enrichment analysis and visualization by interacting with ToppGene, downloading the functional enrichment dataframes, and using R environment to visualize the final results.

AVAILABILITY AND IMPLEMENTATION

Code and documentation are currently available at https://github.com/BioinformaticsMUSC/scToppR.

摘要

动机

scToppR 包提供了一个从 R 程序/脚本到 ToppGene 数据库的接口,可完全访问/控制数据库进行功能富集分析,而无需在其网站(https://toppgene.cchmc.org/)上进行主动交互。

结果

该库通过与 ToppGene 交互、下载功能富集数据框以及使用 R 环境来可视化最终结果,促进了功能富集分析和可视化。

可用性和实现

代码和文档目前可在 https://github.com/BioinformaticsMUSC/scToppR 上获得。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6252/11552619/1535b4534cf8/btae582f1.jpg

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