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噬菌体引导的纳米载体:对抗细菌病原体的精准策略。

Phage-guided nanocarriers: a precision strategy against bacterial pathogens.

作者信息

Ahmed Temoor, Xu Xinyan, Noman Muhammad, Wang Qi, Li Bin

机构信息

State Key Laboratory of Rice Biology and Breeding, Ministry of Agriculture Key Laboratory of Molecular Biology of Crop Pathogens and Insects, Zhejiang Key Laboratory of Biology and Ecological Regulation of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou 310058, China; Xianghu Laboratory, Hangzhou 311231, China; Department of Life Sciences, Western Caspian University, Baku, Azerbaijan.

State Key Laboratory of Rice Biology and Breeding, Ministry of Agriculture Key Laboratory of Molecular Biology of Crop Pathogens and Insects, Zhejiang Key Laboratory of Biology and Ecological Regulation of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou 310058, China.

出版信息

Trends Biotechnol. 2025 Mar;43(3):494-497. doi: 10.1016/j.tibtech.2024.09.002. Epub 2024 Sep 27.

Abstract

Bacterial infections pose a major threat to human health. Here, we describe the recent development of phage-guided therapeutic agent-loaded engineered nanomaterials for precise elimination of bacterial pathogens. This forum highlights the underexplored potential of bioinspired nano-enabled strategies for managing bacterial infections in a precise and safe manner.

摘要

细菌感染对人类健康构成重大威胁。在此,我们描述了用于精确消除细菌病原体的噬菌体引导的负载治疗剂的工程纳米材料的最新进展。本次论坛强调了受生物启发的纳米技术策略在精确、安全地控制细菌感染方面尚未得到充分探索的潜力。

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