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上颈椎硬膜外脓肿,强调糖尿病是危险因素:病例报告。

Upper cervical epidural abscess with emphasis on diabetes as a risk factor: a case report.

机构信息

Department of Surgery, Doctor Sulaiman Al-Habib Medical Group, Buraidah, Qassim, Saudi Arabia.

Department of Medicine, Doctor Sulaiman Al-Habib Medical Group, Buraidah, Qassim, Saudi Arabia.

出版信息

BMC Neurol. 2024 Sep 28;24(1):361. doi: 10.1186/s12883-024-03831-9.

DOI:10.1186/s12883-024-03831-9
PMID:39342124
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11437724/
Abstract

BACKGROUND

An upper cervical spine epidural abscess (UCEA) is an epidural abscess that develops in the area between the occiput and the second cervical spine (axis). It is a rare diagnosis that carries the risk of instability of the atlantoaxial joint, and its management is not well-defined. It is known that the skin is the most common source of infection, and that diabetes mellitus (DM) is the most frequently reported risk factor. In this case, we present a patient diagnosed with UCEA, who achieved full neurological recovery postoperatively despite having neurological deficits for over five days prior to surgery.

CASE PRESENTATION

We report the case of a 56-year-old male patient with no history of any prior medical conditions, who presented with headache, neck pain, and weakness of the left side. The weakness started approximately three days prior to his presentation. His initial work up revealed hyperglycemia and elevated HbA1c of 86 mmol/mol (10%). Magnetic resonance imaging (MRI) of the cervical spine revealed spondylitis of the C2 spine with an abscess at the craniocervical junction. He underwent a two-staged surgical approach: decompression and stabilisation. The patient achieved full motor recovery approximately three months postoperatively.

CONCLUSIONS

We recommend screening for DM when a spinal epidural abscess (SEA) is diagnosed without readily identifiable risk factors. The optimal management in most SEA cases is surgical, which is particularly true for UCEA because of the risk of atlantoaxial joint instability. Full neurological recovery is possible even when the patient has been having deficits for more than five days.

摘要

背景

颈椎上硬膜外脓肿(UCEA)是一种发生在枕骨和第二颈椎(枢椎)之间的硬膜外脓肿。这是一种罕见的诊断,存在寰枢关节不稳定的风险,其治疗方法尚未明确。已知皮肤是最常见的感染源,糖尿病(DM)是最常报告的危险因素。在此病例中,我们报告了一例 UCEA 患者,尽管在手术前有超过五天的神经功能缺损,但术后仍完全恢复了神经功能。

病例介绍

我们报告了一例 56 岁男性患者,无任何既往病史,因头痛、颈部疼痛和左侧无力就诊。无力症状大约在他就诊前三天开始出现。他的初始检查结果显示血糖升高和糖化血红蛋白(HbA1c)升高至 86 mmol/mol(10%)。颈椎磁共振成像(MRI)显示 C2 脊柱的脊椎炎和颅颈交界处的脓肿。他接受了两阶段的手术治疗:减压和稳定。术后大约三个月,患者实现了完全运动功能恢复。

结论

我们建议在没有明显危险因素的情况下诊断出脊髓硬膜外脓肿(SEA)时筛查 DM。大多数 SEA 病例的最佳治疗方法是手术,对于 UCEA 尤其如此,因为存在寰枢关节不稳定的风险。即使患者有超过五天的神经功能缺损,也有可能完全恢复神经功能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2409/11437724/10addf068a74/12883_2024_3831_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2409/11437724/6c95c6e09ace/12883_2024_3831_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2409/11437724/c1bc99d9e965/12883_2024_3831_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2409/11437724/10addf068a74/12883_2024_3831_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2409/11437724/6c95c6e09ace/12883_2024_3831_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2409/11437724/c1bc99d9e965/12883_2024_3831_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2409/11437724/10addf068a74/12883_2024_3831_Fig3_HTML.jpg

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本文引用的文献

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Cervical Spinal Epidural Abscess: Diagnosis, Treatment, and Outcomes: A Case Series and a Literature Review.颈椎硬膜外脓肿:诊断、治疗及预后:病例系列报告与文献综述
J Clin Med. 2023 Jul 5;12(13):4509. doi: 10.3390/jcm12134509.
2
Abridged for Primary Care Providers.为初级保健提供者节略。
Clin Diabetes. 2022 Winter;41(1):4-31. doi: 10.2337/cd23-as01. Epub 2022 Dec 12.
3
Diabetes Mellitus and Bell's Palsy.糖尿病与贝尔氏麻痹。
Curr Diabetes Rev. 2023;19(1):e080322201913. doi: 10.2174/1573399818666220308161023.
4
Indicators of atlantoaxial instability.寰枢椎不稳的指标。
J Craniovertebr Junction Spine. 2021 Apr-Jun;12(2):103-106. doi: 10.4103/jcvjs.jcvjs_55_21. Epub 2021 Jun 10.
5
Peripheral facial nerve palsy associated with COVID-19.与 COVID-19 相关的周围性面神经麻痹。
J Neurovirol. 2020 Dec;26(6):941-944. doi: 10.1007/s13365-020-00912-6. Epub 2020 Oct 2.
6
Diagnosis, and Treatment of Cervical Epidural Abscess and/or Cervical Vertebral Osteomyelitis with or without Retropharyngeal Abscess; A Review.伴有或不伴有咽后脓肿的颈椎硬膜外脓肿和/或颈椎骨髓炎的诊断与治疗;综述
Surg Neurol Int. 2020 Jun 20;11:160. doi: 10.25259/SNI_294_2020. eCollection 2020.
7
Brain and Spinal Epidural Abscess.脑和脊髓硬膜外脓肿
Continuum (Minneap Minn). 2018 Oct;24(5, Neuroinfectious Disease):1327-1348. doi: 10.1212/CON.0000000000000649.
8
Risk of Infection in Type 1 and Type 2 Diabetes Compared With the General Population: A Matched Cohort Study.1 型和 2 型糖尿病与普通人群相比的感染风险:一项匹配队列研究。
Diabetes Care. 2018 Mar;41(3):513-521. doi: 10.2337/dc17-2131. Epub 2018 Jan 12.
9
Upper Cervical Epidural Abscess in Clinical Practice: Diagnosis and Management.临床实践中的上颈椎硬膜外脓肿:诊断与处理。
Global Spine J. 2016 Jun;6(4):383-93. doi: 10.1055/s-0035-1565260. Epub 2015 Oct 13.
10
A three-dimensional study of the atlantodental interval in a normal Chinese population using reformatted computed tomography.一项使用重组计算机断层扫描对正常中国人群寰齿间隙进行的三维研究。
Surg Radiol Anat. 2011 Nov;33(9):801-6. doi: 10.1007/s00276-011-0817-7. Epub 2011 May 6.