Laboratory of Clinical Research in Neuroinfections (LAPCLIN-NEURO), Evandro Chagas National Institute of Infectious Diseases (INI), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, Brazil.
Neurology Section, Hospital Universitário Clementino Fraga Filho, The Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil.
J Neurovirol. 2020 Dec;26(6):941-944. doi: 10.1007/s13365-020-00912-6. Epub 2020 Oct 2.
COVID-19 pandemic revealed several neurological syndromes related to this infection. We describe the clinical, laboratory, and radiological features of eight patients with COVID-19 who developed peripheral facial palsy during infection. In three patients, facial palsy was the first symptom. Nerve damage resulted in mild dysfunction in five patients and moderate in three. SARS-Cov-2 was not detected in CSF by PCR in any of the samples. Seven out of eight patients were treated with steroids and all patients have complete or partial recovery of the symptoms. Peripheral facial palsy should be added to the spectrum of neurological manifestations associated with COVID-19.
COVID-19 大流行揭示了几种与该感染相关的神经系统综合征。我们描述了 8 例 COVID-19 患者在感染期间发生周围性面瘫的临床、实验室和影像学特征。在 3 例患者中,面瘫是首发症状。神经损伤导致 5 例患者轻度功能障碍,3 例患者中度功能障碍。PCR 检测所有样本的 CSF 中均未检测到 SARS-CoV-2。8 例患者中有 7 例接受了类固醇治疗,所有患者的症状均完全或部分恢复。周围性面瘫应添加到与 COVID-19 相关的神经表现谱中。