Beyaz Ferhat, Verhoeven Roel L J, Hoogerwerf Nico, Mourisse Jo M J, van der Heijden Erik H F M
Department of Pulmonary Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.
Department of Anesthesiology, Pain and Palliative Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
Respiration. 2025;104(3):216-228. doi: 10.1159/000541691. Epub 2024 Sep 28.
Cone beam computed tomography-guided navigation bronchoscopy (CBCT-NB) with augmented fluoroscopy (AF) guidance represents a minimally invasive endobronchial technique for diagnosing small, peripheral pulmonary lesions. This approach is characterized by its high diagnostic accuracy and low complication risk. Current pilot trials are exploring the application of localized therapies using this innovative approach. This report aims to provide a detailed procedural guide for performing CBCT-NB with AF guidance as the only tool for navigation and image guided biopsy.
We outline the procedural steps involved in the CBCT-NB procedure for diagnosing peripheral pulmonary lesions, supported by specific intra-procedural clinical video footage. The steps include (1) preprocedural considerations, (2) a detailed procedural workflow encompassing navigation to the target lesion, (3) position confirmation and tissue acquisition, and (4) postprocedural follow-up.
CBCT-NB with AF guidance is a safe and precise stand-alone navigation modality that offers high-resolution real-time 3D imaging, enhancing the diagnosis and potential treatment of peripheral pulmonary nodules.
Cone beam computed tomography-guided navigation bronchoscopy (CBCT-NB) with augmented fluoroscopy (AF) guidance represents a minimally invasive endobronchial technique for diagnosing small, peripheral pulmonary lesions. This approach is characterized by its high diagnostic accuracy and low complication risk. Current pilot trials are exploring the application of localized therapies using this innovative approach. This report aims to provide a detailed procedural guide for performing CBCT-NB with AF guidance as the only tool for navigation and image guided biopsy.
We outline the procedural steps involved in the CBCT-NB procedure for diagnosing peripheral pulmonary lesions, supported by specific intra-procedural clinical video footage. The steps include (1) preprocedural considerations, (2) a detailed procedural workflow encompassing navigation to the target lesion, (3) position confirmation and tissue acquisition, and (4) postprocedural follow-up.
CBCT-NB with AF guidance is a safe and precise stand-alone navigation modality that offers high-resolution real-time 3D imaging, enhancing the diagnosis and potential treatment of peripheral pulmonary nodules.
锥束计算机断层扫描引导下的导航支气管镜检查（CBCT-NB）联合增强荧光透视（AF）引导是一种用于诊断小的外周肺部病变的微创支气管内技术。该方法具有诊断准确性高和并发症风险低的特点。目前的试点试验正在探索使用这种创新方法进行局部治疗的应用。本报告旨在提供一份详细的操作指南，用于以AF引导作为唯一的导航和图像引导活检工具来实施CBCT-NB。
我们概述了在CBCT-NB程序中诊断外周肺部病变所涉及的操作步骤，并辅以特定的术中临床视频片段。这些步骤包括（1）术前考虑，（2）包含导航至目标病变的详细操作流程，（3）位置确认和组织获取，以及（4）术后随访。
AF引导下的CBCT-NB是一种安全且精确的独立导航方式，可提供高分辨率实时三维成像，增强对外周肺结节的诊断和潜在治疗效果。
锥束计算机断层扫描引导下的导航支气管镜检查（CBCT-NB）联合增强荧光透视（AF）引导是一种用于诊断小的外周肺部病变的微创支气管内技术。该方法具有诊断准确性高和并发症风险低的特点。目前的试点试验正在探索使用这种创新方法进行局部治疗的应用。本报告旨在提供一份详细的操作指南，用于以AF引导作为唯一的导航和图像引导活检工具来实施CBCT-NB。
我们概述了在CBCT-NB程序中诊断外周肺部病变所涉及的操作步骤，并辅以特定的术中临床视频片段。这些步骤包括（1）术前考虑，（2）包含导航至目标病变的详细操作流程，（3）位置确认和组织获取，以及（4）术后随访。
AF引导下的CBCT-NB是一种安全且精确的独立导航方式，可提供高分辨率实时三维成像，增强对外周肺结节的诊断和潜在治疗效果。
