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Asiaticoside-Nitric Oxide Hydrogel accelerates diabetic wound healing via miR-21-mediated DNA demethylation.

作者信息

Chen Jitao, Deng Junyu, Tang Ming, Nie Xuqiang

机构信息

College of Pharmacy, Zunyi Medical University, Zunyi, 563000, China; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, 563000, China.

Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, 38105, United States.

出版信息

Asian J Surg. 2024 Sep 28. doi: 10.1016/j.asjsur.2024.09.109.

DOI:10.1016/j.asjsur.2024.09.109
PMID:39343674
Abstract
摘要

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Asiaticoside-Nitric Oxide Hydrogel accelerates diabetic wound healing via miR-21-mediated DNA demethylation.积雪草苷-一氧化氮水凝胶通过miR-21介导的DNA去甲基化加速糖尿病伤口愈合。
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Asiaticoside-nitric oxide synergistically accelerate diabetic wound healing by regulating key metabolites and SRC/STAT3 signaling.积雪草苷-一氧化氮通过调节关键代谢物和SRC/STAT3信号通路协同促进糖尿病伤口愈合。
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