Cicciarelli J C, Terasaki P I, Chia D, Barnett E V, Mickey M R, Prince S, Iwaki Y, Shirahama S
Clin Exp Immunol. 1979 Oct;38(1):181-5.
A micro-latex fixation test (LFT) for the determination of rheumatoid factor (RF) is presented. Its advantages compared to similar tests are greater precision, simplicity, increased sensitivity, lower cost, reproducibility and adaptibility to large-scale testing. Micro-LFT titres are presented from a wide range of sample populations. The majority of normal samples show measureable titres whereas rheumatoid patients show high titres. A large sampling of pre- and post-transplant sera from kidney patients was studied and the micro-LFT titres were in the range of normal persons. The transplant sera were tested for lymphocytotoxic antibodies and no correlation was observed with the micro-LFT titres.
本文介绍了一种用于测定类风湿因子(RF)的微量乳胶凝集试验(LFT)。与类似试验相比,其优点在于精度更高、操作简单、灵敏度提高、成本更低、可重复性强且适用于大规模检测。文中给出了来自广泛样本群体的微量LFT滴度。大多数正常样本显示出可测量的滴度,而类风湿患者显示出高滴度。对大量肾移植患者移植前后的血清进行了研究,其微量LFT滴度在正常人范围内。对移植血清进行了淋巴细胞毒性抗体检测,未观察到与微量LFT滴度有相关性。