Department of Cardiology, Maastricht University Medical Center and Cardiovascular Research Institute Maastricht, Universiteitssingel 50, 6229 ER Maastricht, The Netherlands.
Department of Clinical Sciences, Karolinska Institutet, Danderyd University Hospital, Stockholm, Sweden.
Europace. 2024 Oct 3;26(10). doi: 10.1093/europace/euae247.
Reduction of atrial fibrillation (AF) burden is the preferred outcome measure over categorical AF rhythm recurrence after AF ablation. In this sub-analysis of the TeleCheck-AF project, we tested the feasibility of smartphone app-based approximation of time spent with AF and/or symptoms.
Patients scheduled for at least one teleconsultation during the 12-month follow-up after AF ablation were instructed to use a smartphone photoplethysmography-based application for simultaneous symptom and rhythm monitoring three times daily for 1 week. Proxies of time spent with AF and/or symptoms (% recordings, load, and % days), temporal aggregation of AF and/or symptoms (density), and symptom-rhythm correlation (SRC) were assessed. In total, 484 patients (60% male, 62 ± 9.9 years) were included. Adherence, motivation, and patient satisfaction were high. %AF recordings, AF load, and %AF days (rs = 0.88-0.95) and %symptom recordings, symptom load, and %symptom days (rs = 0.95-0.98) showed positive correlations. The SRC correlated negatively with time spent with symptoms (rs = -0.65-0.90) and with time spent with AF (rs = -0.31-0.34). In patients with paroxysmal AF before ablation and AF during the monitoring period, 87% (n = 39/44) had a low-density score <50% ('paroxysmal AF pattern') while 5% (n = 2/44) had a high-density score >90% ('persistent AF pattern'). Corresponding numbers for patients with persistent AF before ablation were 48% (n = 11/23) and 43% (n = 10/23), respectively.
On-demand, app-based simultaneous rhythm and symptom assessment provides objective proxies of time spent with AF and/or symptoms and SRC, which may assist in assessing AF and symptom outcomes after AF ablation.
在房颤消融后,房颤(AF)负荷的减少是优于房颤节律复发的首选疗效指标。在 TeleCheck-AF 项目的这项亚组分析中,我们测试了基于智能手机应用程序来近似 AF 和/或症状发作时间的可行性。
在消融后 12 个月的随访期间至少安排了 1 次远程咨询的患者,被指示使用基于智能手机光电容积脉搏波的应用程序,每天进行 3 次、每次持续 1 周的同步症状和节律监测。评估了 AF 和/或症状发作时间的近似值(%记录、负荷和%天数)、AF 和/或症状的时间聚集(密度)以及症状-节律相关性(SRC)。总共纳入了 484 名患者(60%为男性,62±9.9 岁)。患者的依从性、积极性和满意度均很高。%AF 记录、AF 负荷和%AF 天数(rs=0.88-0.95)和%症状记录、症状负荷和%症状天数(rs=0.95-0.98)之间存在正相关。SRC 与症状发作时间(rs=-0.65-0.90)和 AF 发作时间(rs=-0.31-0.34)呈负相关。在消融前为阵发性 AF 且监测期间存在 AF 的患者中,87%(n=39/44)的低密度评分<50%(“阵发性 AF 模式”),而 5%(n=2/44)的低密度评分>90%(“持续性 AF 模式”)。在消融前为持续性 AF 的患者中,相应的数字分别为 48%(n=11/23)和 43%(n=10/23)。
基于需求的、基于应用程序的同步节律和症状评估提供了 AF 和/或症状发作时间和 SRC 的客观近似值,这可能有助于评估 AF 消融后的 AF 和症状结果。