Martino P, Cervigni M, Cores E V, Cossini F, Román K, Cuesta C, Esnaola Y Rojas M M, Graviotto G, Gallegos M, Politis D
Consejo Nacional de Investigaciones Científicas y Técnicas de Argentina (CONICET), Buenos Aires, Argentina.
Universidad Nacional de San Luis, San Luis, Argentina.
Rev Neurol. 2024 Oct 1;79(7):187-197. doi: 10.33588/rn.7907.2024171.
The global burden of dementia will continue to increase and Latin America will be one of the most affected regions. It is urgent to have new and better cognitive screening tools. There are few screenings composed entirely of auditory-verbal items and even more so for Argentine culture. The objective was to build and validate a test for verbal auditory screening of cognitive alterations (CAVAC) in Argentina.
Evidence based in test content was analyzed through 16 experts collaborated. In addition, evidence based on relationships to other variables, internal consistency and the ability to discriminate between cognitively healthy subjects, Mild Cognitive Impairment (MCI) and dementia were investigated. The CAVAC was applied to 316 Argentines (M age = 68,5). Volunteers from the general population and patients from neurology services from two Argentine hospitals participated.
The CAVAC test explores orientation/attention, memory/learning, language and executive functions, and is administered in 10 minutes with a score of 0 to 30. Aiken's V coefficient was satisfactory for all items. The CAVAC achieved a high correlation with the Mini Mental (0.762) and an acceptable Cronbach's alpha (0.746). The CAVAC score differs between controls, mild cognitive impairment (MCI) and dementia, and the ROC curves reveal adequate area values ??to discriminate MCI and dementia (>0.7), and cut-off points with good sensitivity-specificity.
A new auditory-verbal test is made available for the screening of cognitive alterations with acceptable evidence of validity, good reliability, with the capacity to identify MCI and dementia, and free of charge for use.
痴呆症的全球负担将持续增加,拉丁美洲将是受影响最严重的地区之一。迫切需要新的、更好的认知筛查工具。完全由听觉语言项目组成的筛查很少,针对阿根廷文化的更是如此。目的是构建并验证一项用于阿根廷认知功能改变的言语听觉筛查测试(CAVAC)。
通过16位专家合作分析基于测试内容的证据。此外,还研究了基于与其他变量的关系、内部一致性以及区分认知健康受试者、轻度认知障碍(MCI)和痴呆症的能力的证据。CAVAC应用于316名阿根廷人(平均年龄 = 68.5岁)。来自普通人群的志愿者和阿根廷两家医院神经科服务的患者参与其中。
CAVAC测试涵盖定向/注意力、记忆/学习、语言和执行功能,测试时间为10分钟,得分范围为0至30分。所有项目的艾肯V系数均令人满意。CAVAC与简易精神状态检查表(Mini Mental)高度相关(0.762),且具有可接受的克朗巴哈系数(0.746)。CAVAC得分在对照组、轻度认知障碍(MCI)和痴呆症之间存在差异,ROC曲线显示有足够的面积值来区分MCI和痴呆症(>0.7),且具有良好敏感性 - 特异性的截断点。
一种新的听觉语言测试可用于认知功能改变的筛查,具有可接受的效度证据、良好的信度,能够识别MCI和痴呆症,且可免费使用。