Nicotine gum vs. placebo gum: comparisons of withdrawal symptoms and success rates.

Our data and that of researchers in the area clearly provide evidence for nicotine-specific withdrawal and its relief with nicotine gum. In addition, outcome efficacy is enhanced when nicotine gum is combined with behavioral treatment. Nicotine gum appears to be valuable both as a systematic tool and as a means of combatting short- and long-term nicotine seeking that contribute to maintenance of smoking and the inability to quit.