Perone Francesco, Spadafora Luigi, Pratesi Alessandra, Nicolaio Giulia, Pala Barbara, Franco Giulia, Ruzzolini Matteo, Ambrosetti Marco
Cardiac Rehabilitation Unit, Rehabilitation Clinic "Villa delle Magnolie", 81020, Castel Morrone, Caserta, Italy.
Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy.
Int J Cardiol Cardiovasc Risk Prev. 2024 Sep 5;23:200331. doi: 10.1016/j.ijcrp.2024.200331. eCollection 2024 Dec.
The patient with obesity is at risk of developing cardiovascular disease and risk factors. Obesity negatively impacts prognosis and increases cardiovascular morbidity and mortality. Therefore, a comprehensive risk assessment is needed to define the cardiovascular risk of the patient and, thus, a tailored management and treatment. Chronic and successful management of these patients involves the evaluation of the various therapeutic strategies available (comprehensive lifestyle intervention, weight-loss medications, and bariatric surgery) and the diagnosis and treatment of cardiovascular complications (coronary artery disease, heart failure, and atrial fibrillation). Cardiac rehabilitation in patients with obesity is showing beneficial effect and a positive impact on weight loss, cardiovascular risk factors, mental health, functional capacity, and adherence to lifestyle interventions and pharmacological treatment. Long-term weight loss and maintenance represent a key objective during the management of the patient with obesity to reduce the risk of future adverse events. Multidisciplinary management and interventions are necessary to prevent and reduce overall cardiovascular risk and mortality. The aim of our review is to propose a comprehensive, critical and updated overview regarding risk assessment, physical activity, and the management of cardiovascular complications in patient with obesity.
肥胖患者有发生心血管疾病及风险因素的风险。肥胖会对预后产生负面影响,并增加心血管疾病的发病率和死亡率。因此,需要进行全面的风险评估,以确定患者的心血管风险,从而制定个性化的管理和治疗方案。对这些患者进行长期且成功的管理,包括评估各种可用的治疗策略(全面的生活方式干预、减肥药物和减肥手术)以及心血管并发症(冠状动脉疾病、心力衰竭和心房颤动)的诊断和治疗。肥胖患者的心脏康复显示出有益效果,对体重减轻、心血管风险因素、心理健康、功能能力以及对生活方式干预和药物治疗的依从性都有积极影响。长期的体重减轻和维持是肥胖患者管理期间的关键目标,以降低未来不良事件的风险。多学科管理和干预对于预防和降低总体心血管风险及死亡率是必要的。我们综述的目的是就肥胖患者的风险评估、体育活动和心血管并发症的管理提出全面、批判性和最新的概述。