Chawla Riddhi, Jahagirdar Abhishek, Riba Happy, Satheesh Tharini, Somwanshi Pratiksha, Behera Shiba Brata, Gulia Sunil K
School of Dentistry, Central Asian University, Tashkent, Uzbekistan.
DDS, MDS, Associate Dentist, Lubbock, Texas, United States.
J Pharm Bioallied Sci. 2024 Jul;16(Suppl 3):S2631-S2633. doi: 10.4103/jpbs.jpbs_390_24. Epub 2024 Jul 31.
A common sleep problem linked to poor cardiovascular outcomes and death is " (SL)." Nevertheless, little is known about how SL affects cardiovascular health in the long run. The purpose of this research was to investigate the relationship between a tertiary care center's long-term cohort's cardiovascular morbidity and mortality and the severity of their SL.
Between January 1, 2010, and December 31, 2020, 500 individuals at a tertiary care facility who had been diagnosed with SL participated in this retrospective cohort research. Electronic medical records were used to collect patient data, which were then examined for cardiovascular outcomes, treatment methods, comorbidities, sleep research findings, and demographics. Heart failure, myocardial infarction, stroke, and cardiovascular-related mortality were among the cardiovascular events that were noted throughout the follow-up period, and the severity of SL was classified using the "-."
Of the 500 patients in the cohort, 60% were men and the mean age was 55.7 years. Fifty percent of people had one or more cardiovascular risk factors, including diabetes, high blood pressure, and smoking. During the course of the follow-up, 100 cardiovascular-related fatalities were reported, and 40% of patients had at least one cardiovascular event. The severity of SL was shown to be positively correlated with the occurrence of cardiovascular events (16.7% in mild, 25% in moderate, and 40% in severe SL, < 0.05).
In a cohort of patients receiving tertiary care, this research shows a substantial correlation between the severity of SL and cardiovascular morbidity and death. It is crucial to identify and treat SL early on to reduce cardiovascular risks and enhance patient outcomes. To further understand the underlying processes and develop treatment approaches for people with cardiovascular comorbidities and SL, more research is necessary.
一种与不良心血管结局及死亡相关的常见睡眠问题是“睡眠呼吸暂停（SL）”。然而，从长远来看，关于睡眠呼吸暂停如何影响心血管健康，人们知之甚少。本研究的目的是调查一家三级医疗中心的长期队列中，心血管发病率和死亡率与他们睡眠呼吸暂停严重程度之间的关系。
在2010年1月1日至2020年12月31日期间，一家三级医疗机构中500名被诊断患有睡眠呼吸暂停的个体参与了这项回顾性队列研究。使用电子病历收集患者数据，然后对这些数据进行心血管结局、治疗方法、合并症、睡眠研究结果及人口统计学方面的检查。在整个随访期间记录的心血管事件包括心力衰竭、心肌梗死、中风及心血管相关死亡，睡眠呼吸暂停的严重程度使用“-”进行分类。
该队列中的500名患者中，60%为男性，平均年龄为55.7岁。50%的人有一个或多个心血管危险因素，包括糖尿病、高血压和吸烟。在随访过程中，报告了100例心血管相关死亡，40%的患者至少发生过一次心血管事件。睡眠呼吸暂停的严重程度与心血管事件的发生呈正相关（轻度睡眠呼吸暂停患者中为16.7%，中度为2
