Sivaram J, Bothra Himanshu, Kumar Pushpendra, Khalid Mohammed Kinaan, Panja Supantha, Shashank Chapala, Satheesh Tharini
Department of Orthopeadics, Government Sivagangai Medical College, Sivagangai, Tamil Nadu, India.
Orthopaedic, MGM Medical College, Aurangabad, Maharashtra, India.
J Pharm Bioallied Sci. 2024 Jul;16(Suppl 3):S2552-S2554. doi: 10.4103/jpbs.jpbs_237_24. Epub 2024 Jun 7.
While short-term outcomes of total knee arthroplasty (TKA) have been extensively studied, there is a need for longstanding assessments to understand the enduring impact of the procedure on patient well-being.
A retrospective cohort research to rate the longstanding functional outcomes and quality of life (QoL) in those undergoing primary TKA. Patient-reported outcomes, including SF-36 and EQ-5D scores, were collected at multiple time points postoperatively (1, 5, and 10 years). Objective assessments of functional parameters, i.e., range of motion, gait analysis, and quadriceps strength, were also recorded.
Current findings demonstrate significant improvements in functional outcomes post-TKA, with sustained benefits observed over a 10-year period. Range of motion, gait parameters, and quadriceps strength showed consistent enhancements postoperatively. Moreover, QoL measures, as reflected by SF-36 and EQ-5D scores, exhibited substantial improvements following TKA and remained elevated throughout the follow-up period.
This research highlights the enduring effectiveness of TKA in improving both functional outcomes and QoL in patients with advanced knee arthritis.
虽然全膝关节置换术（TKA）的短期疗效已得到广泛研究，但仍需要长期评估，以了解该手术对患者健康的持久影响。
一项回顾性队列研究，对接受初次TKA的患者的长期功能结局和生活质量（QoL）进行评估。在术后多个时间点（1年、5年和10年）收集患者报告的结局，包括SF-36和EQ-5D评分。还记录了功能参数的客观评估，即活动范围、步态分析和股四头肌力量。
目前的研究结果表明，TKA术后功能结局有显著改善，且在10年期间持续受益。术后活动范围、步态参数和股四头肌力量均持续增强。此外，SF-36和EQ-5D评分反映的QoL指标在TKA术后有显著改善，并在整个随访期内保持升高。
本研究强调了TKA在改善晚期膝关节炎患者功能结局和QoL方面的持久有效性。
