Kukreja Pankaj, Grewal Raman, Tejaswee Annaluru Sri Sasank, Sharma Sanjeev, Maini Anuj Paul, Chandran Thara, Gulia Sunil Kumar
Department of Biomedical Dental Sciences, Faculty of Dentistry, Al-Baha University, Al-Aqiq Campus, Kingdom of Saudi Arabia.
Advance Cancer Institute, Bathinda, Punjab, India.
J Pharm Bioallied Sci. 2024 Jul;16(Suppl 3):S2440-S2442. doi: 10.4103/jpbs.jpbs_297_24. Epub 2024 Jul 31.
Because of its high rates of morbidity and death, oral squamous cell carcinoma (OSCC) poses a serious threat to world health. To maximize patient care and direct clinical decision-making, it is important to comprehend treatment results and survival rates.
Treatment results and survival rates for OSCC patients treated at a tertiary care facility between 2010 and 2022 were assessed in this retrospective research. Demographic data, tumor features, treatment options, and follow-up results were all included in the data. The relationships between treatment methods and survival rates were evaluated by statistical analysis.
There were 107 OSCC patients in all. Compared to radiation and chemotherapy, surgery had reduced recurrence rates and greater overall survival rates as the most common treatment option. There were notable variations in survival rates across the various treatment regimens ( < 0.05).
Surgery is the mainstay. Adjuvant treatments, however, are complementary in the management of illness. The significance of customized treatment strategies based on unique patient attributes and tumor features is highlighted by this study in order to maximize results for patients with OSCC. To confirm these results and investigate cutting-edge treatment approaches, more investigation is necessary.
口腔鳞状细胞癌（OSCC）因其高发病率和死亡率，对全球健康构成严重威胁。为了最大限度地提高患者护理水平并指导临床决策，了解治疗结果和生存率非常重要。
本回顾性研究评估了2010年至2022年在一家三级医疗机构接受治疗的OSCC患者的治疗结果和生存率。数据包括人口统计学数据、肿瘤特征、治疗选择和随访结果。通过统计分析评估治疗方法与生存率之间的关系。
共有107例OSCC患者。作为最常见的治疗选择，与放疗和化疗相比，手术降低了复发率，提高了总生存率。不同治疗方案的生存率存在显著差异（<0.05）。
手术是主要治疗方法。然而，辅助治疗在疾病管理中具有辅助作用。本研究强调了基于患者独特属性和肿瘤特征制定个性化治疗策略的重要性，以便为OSCC患者实现最佳治疗效果。为了证实这些结果并研究前沿治疗方法，还需要更多的研究。
