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柠檬草提取物(香茅)纳米乳液的表征及其作为丙烯酸树脂抗生物膜剂的应用

Characterization of Lemongrass Extract (Cymbopagon citratus) Nanoemulsion and Its Application as an Antibiofilm Agent in Acrylic Resin.

作者信息

Sugiaman Vinna K, Saputri Rosalina I, Naliani Silvia, Wibisono Jane A V, Demolsky Wayan L, Widowati Wahyu, Novianto Agung

机构信息

Department of Oral Biology, Faculty of Dentistry, Maranatha Christian University, Bandung, West Java, Indonesia.

Department of Biomedical Science, Faculty of Dentistry, Maranatha Christian University, Bandung, West Java, Indonesia.

出版信息

J Pharm Bioallied Sci. 2024 Jul;16(Suppl 3):S2715-S2717. doi: 10.4103/jpbs.jpbs_418_24. Epub 2024 Jul 31.

DOI:10.4103/jpbs.jpbs_418_24
PMID:39346363
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11426857/
Abstract

BACKGROUND

An antimicrobial agent is needed for denture cleaning, such as lemongrass (LG), which has a bioactive antimicrobial component.

METHODS

This research analyzed LG extract nanoparticles with a particle size analyzer, ZPA, and biofilm formation inhibition on resin acrylic surfaces.

RESULTS

We found that there is high stability in nanoparticle size, while other concentrations, including chlorhexidine as a positive control, did not show any statistical differences.

CONCLUSION

Lemongrass oil nanoemulsion has proved to be an antibiofilm and effective as a denture cleaning agent because of its ability to inhibit Streptococcus mutans and Candida albicans growth.

摘要

背景

义齿清洁需要一种抗菌剂,例如具有生物活性抗菌成分的柠檬草(LG)。

方法

本研究使用粒度分析仪、ZPA分析LG提取物纳米颗粒,并分析其对树脂丙烯酸表面生物膜形成的抑制作用。

结果

我们发现纳米颗粒大小具有高稳定性,而包括作为阳性对照的洗必泰在内的其他浓度均未显示出任何统计学差异。

结论

柠檬草油纳米乳剂已被证明具有抗生物膜作用,并且由于其能够抑制变形链球菌和白色念珠菌的生长,因此可作为一种有效的义齿清洁剂。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73f0/11426857/fa1b998a9e96/JPBS-16-2715-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73f0/11426857/09f2d9b1e074/JPBS-16-2715-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73f0/11426857/fa1b998a9e96/JPBS-16-2715-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73f0/11426857/09f2d9b1e074/JPBS-16-2715-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73f0/11426857/fa1b998a9e96/JPBS-16-2715-g002.jpg

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本文引用的文献

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Molecules. 2022 Jul 31;27(15):4895. doi: 10.3390/molecules27154895.
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Host's Immunity and Species Associated with Denture Stomatitis: A Narrative Review.宿主免疫与义齿性口炎相关物种:一项叙述性综述。
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Synergistic interaction of eugenol and antimicrobial drugs in eradication of single and mixed biofilms of Candida albicans and Streptococcus mutans.
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Antimicrobial Activity of Some Essential Oils-Present Status and Future Perspectives.某些精油的抗菌活性——现状与未来展望
Medicines (Basel). 2017 Aug 8;4(3):58. doi: 10.3390/medicines4030058.
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Efficacy of Neem Extract and Three Antimicrobial Agents Incorporated into Tissue Conditioner in Inhibiting the Growth of and .印楝提取物和三种抗菌剂添加到组织调理剂中对[具体细菌名称1]和[具体细菌名称2]生长的抑制效果。 (你原文中“and.”后面应该有具体细菌名称,这里按格式补充了)
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The effects of silane-SiO2 nanocomposite films on Candida albicans adhesion and the surface and physical properties of acrylic resin denture base material.硅烷 - 二氧化硅纳米复合膜对白色念珠菌黏附以及丙烯酸树脂义齿基托材料表面和物理性能的影响
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Efficacy of denture cleansers in reducing microbial counts from removable partial dentures: a short-term clinical evaluation.义齿清洁剂减少可摘局部义齿微生物数量的效果:一项短期临床评估。
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