Janardhan Karthika, Parikh Hiral
Department of Periodontics, Narsinhbhai Patel Dental College and Hospital, Sankalchand Patel University, Visnagar, Gujarat, India.
J Pharm Bioallied Sci. 2024 Jul;16(Suppl 3):S2773-S2775. doi: 10.4103/jpbs.jpbs_387_24. Epub 2024 Jul 31.
One common inflammatory illness that affects periodontal tissues is chronic periodontitis. By lowering inflammation and getting rid of periodontal bacteria, nonsurgical periodontal management is essential for treating chronic periodontitis. The objective of this study was to evaluate the effectiveness of chlorhexidine and feracrylum in nonsurgical periodontal management for persistent periodontitis.
As part of their periodontal therapy, 50 patients with a diagnosis of chronic periodontitis were randomized into two groups: first got chlorhexidine, while other Feracrylum received feracrylum. Microbiological analysis and clinical parameters were measured at baseline and 3 months later.
Clinical metrics showed a considerable improvement in both groups. Comparing feracrylum to chlorhexidine, the former showed stronger antibacterial action against periodontal infections.
For nonsurgical periodontal management of chronic periodontitis, feracrylum shows similar effectiveness to chlorhexidine. Furthermore, feracrylum has better antibacterial activity against pathogens of the periodontal tissues, indicating that it might be used as a substitute antimicrobial agent in periodontal management.
慢性牙周炎是一种影响牙周组织的常见炎症性疾病。通过减轻炎症和清除牙周细菌，非手术牙周治疗对于治疗慢性牙周炎至关重要。本研究的目的是评估洗必泰和铁丙烯在非手术牙周治疗中对持续性牙周炎的有效性。
作为牙周治疗的一部分，50例诊断为慢性牙周炎的患者被随机分为两组：一组接受洗必泰治疗，另一组接受铁丙烯治疗。在基线和3个月后测量微生物分析和临床参数。
临床指标显示两组均有显著改善。与洗必泰相比，铁丙烯对牙周感染显示出更强的抗菌作用。
对于慢性牙周炎的非手术牙周治疗，铁丙烯显示出与洗必泰相似的有效性。此外，铁丙烯对牙周组织病原体具有更好的抗菌活性，表明它可能用作牙周治疗中的替代抗菌剂。
