Liu Sao-Shen, Fu Earl, Tu Hsiao-Pei, Fu Min-Wen, Lin Chia-Te, Shen E-Chin
School of Dentistry, National Defense Medical Center and Tri-Service General Hospital, Taipei, Taiwan, ROC.
Dental Department, Taipei Tzu Chi Hospital, Xindian, New Taipei City, Taiwan, ROC.
J Dent Sci. 2017 Jun;12(2):156-160. doi: 10.1016/j.jds.2016.12.004. Epub 2017 Mar 21.
BACKGROUND/PURPOSE: Periodontal diseases have been considered as a source of oral malodor or halitosis. Improvement of oral malodor in chronic periodontitis patients has recently been observed after nonsurgical periodontal therapy in combination with tongue cleaning and/or chlorhexidine mouth rinsing. The present study, however, evaluated the impact of nonsurgical periodontal therapy alone on the oral malodor in chronic periodontitis patients by comparing the intraoral concentrations of volatile sulfur compounds (VSCs) before and after nonsurgical therapy.
Using a sulfide monitor, the total VSCs in exhaled breath were measured in 80 patients with chronic periodontitis prior to and 1 month after nonsurgical periodontal therapy (re-evaluation phase). Malodor was defined as a VSC score > 75 parts per billion (ppb) and > 110 ppb, respectively.
Significantly lower level of VSCs was recorded at periodontal re-evaluation (55 ± 9.7 ppb) than before treatment (89 ± 16.3 ppb). Before treatment, 27 (34%) patients were considered to have malodor, defined as VSCs > 75 ppb. After treatment, 16 patients (20%) had VSC scores > 75 ppb, including 10 of 27 patients with baseline VSC scores > 75 ppb and six of 53 patients with baseline scores ≤ 75 ppb. The risk of malodor differed significantly before and after treatment (P = 0.035, McNemar's test). However, when malodor was defined as VSCs > 110 ppb, the difference in risk showed only borderline significance (P = 0.077).
On the basis of our findings, we suggest that nonsurgical periodontal therapy has a mild impact on oral malodor.
背景/目的：牙周疾病一直被认为是口腔异味或口臭的一个来源。最近观察到，在非手术牙周治疗联合舌清洁和/或洗必泰漱口水使用后，慢性牙周炎患者的口腔异味有所改善。然而，本研究通过比较非手术治疗前后口腔内挥发性硫化物（VSC）的浓度，评估了单纯非手术牙周治疗对慢性牙周炎患者口腔异味的影响。
使用硫化物监测仪，在80例慢性牙周炎患者非手术牙周治疗前（基线期）和治疗后1个月（重新评估期）测量呼出气体中的总VSC。异味分别定义为VSC评分>75十亿分比（ppb）和>110 ppb。
在牙周重新评估时记录的VSC水平（55±9.7 ppb）显著低于治疗前（89±16.3 ppb）。治疗前，27例（34%）患者被认为有异味，定义为VSC>75 ppb。治疗后，16例患者（20%）的VSC评分>75 ppb，包括27例基线VSC评分>75 ppb患者中的10例和53例基线评分≤75 ppb患者中的6例。治疗前后异味风险有显著差异（P = 0.035，McNemar检验）。然而，当异味定义为VSC>110 ppb时，风险差异仅显示出临界显著性（P = 0.077）。
根据我们的研究结果，我们认为非手术牙周治疗对口腔异味有轻微影响。
