Thongmuang Pimporn, Thongkao Kanittada, Owen Robert Wyn, Sudjaroen Yuttana
College of Allied Health Sciences, Suan Sunandha Rajabhat University, Samut Songkhram, Thailand.
Faculty of Science and Technology, Suan Sunandha Rajabhat University, Bangkok, Thailand.
J Pharm Bioallied Sci. 2024 Jul;16(Suppl 3):S2709-S2711. doi: 10.4103/jpbs.jpbs_421_24. Epub 2024 Jul 31.
Seablite () grows near mangrove forests and shrimp farms on the coast of the Thai Gulf and South of Thailand. Extracts of S. maritima root can relieve or treat some skin symptoms or diseases, and it can be possessed.
The aim of this study was to screen phytochemical constituents of root extract (SMRE) to determine their biological activities related to skincare properties.
Qualitative phytochemical screening was positive for tannins and triterpenes. Total phenolic content (TPC) and total flavonoid content (TFC) were 191.3 ± 3.55 mg of GAE/g and 21.2 ± 2.09 mg of QE/g, respectively. SMRE inhibited the DPPH (2,2-Diphenyl-1-Picrylhydrazyl) radical (IC = 0.25 ± 0.2 mg/ml) and lipid peroxidation (IC = 2.61 ± 0.5 mg/ml). Human skin fibroblasts were increased by 26.58 ± 5.91% after treatment with SMRE (1.0 mg/ml) and exhibited wound healing capacity by narrowing the gap between skin fibroblast clusters.
This study confirms the potential of SMRE for skincare protection which meets the need for traditional uses of plant-derived products for skincare applications.
碱蓬生长在泰国湾沿岸和泰国南部的红树林及虾养殖场附近。海滨碱蓬根提取物可缓解或治疗一些皮肤症状或疾病,且可获取。
本研究旨在筛选海滨碱蓬根提取物(SMRE)的植物化学成分,以确定其与护肤特性相关的生物活性。
植物化学定性筛选显示单宁和三萜呈阳性。总酚含量(TPC)和总黄酮含量(TFC)分别为191.3±3.55毫克没食子酸当量/克和21.2±2.09毫克槲皮素当量/克。SMRE抑制DPPH(2,2-二苯基-1-苦基肼)自由基(IC₅₀ = 0.25±0.2毫克/毫升)和脂质过氧化(IC₅₀ = 2.61±0.5毫克/毫升)。用SMRE(1.0毫克/毫升)处理后人皮肤成纤维细胞增加了26.58±5.91%,并通过缩小皮肤成纤维细胞簇之间的间隙表现出伤口愈合能力。
本研究证实了SMRE在皮肤护理保护方面的潜力,满足了植物源产品用于皮肤护理应用的传统用途需求。